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furfural

flavor and fragrance agents
2D:
3D:
CAS Number: 98-01-1
ECHA EC Number: 202-627-7
FDA UNII: DJ1HGI319P
CoE Number: 2014
Category: flavor and fragrance agents
IUPAC Name: furfural
InChI : InChI=1/C5H4O2/c6-4-5-2-1-3-7-5/h1-4H
Std.InChI: InChI=1S/C5H4O2/c6-4-5-2-1-3-7-5/h1-4H
InChIKey : HYBBIBNJHNGZAN-UHFFFAOYAD
Std.InChIKey: HYBBIBNJHNGZAN-UHFFFAOYSA-N
SMILES : C1=COC(=C1)C=O
MDL: MFCD00003229
Molar Refractivity : 25.30 ± 0.3 cm3 (est)
Parachor : 206.3 ± 4.0 cm3 (est)
Index of Refraction : 1.515 ± 0.02 (est)
Surface Tension : 36.5 ± 3.0 dyne/cm (est)
Density : 1.145 ± 0.06 g/cm3 (est)
Polarizability : 10.03 ± 0.5 10-24cm3 (est)
Fragrance Demo Formulas

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Flavoring:450 furfural
DG SANTE Food Flavourings:13.018 furfural
FEMA Number:2489 furfural
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):98-01-1 ; FURFURAL
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.

Physical Properties:

Appearance:colorless to pale yellow clear oily liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity:1.15600 to 1.16200 @ 25.00 °C.
Pounds per Gallon - (est).: 9.619 to 9.669
Refractive Index:1.52200 to 1.52800 @ 20.00 °C.
Melting Point: -36.00 °C. @ 760.00 mm Hg
Boiling Point: 161.00 to 162.00 °C. @ 760.00 mm Hg
Boiling Point: 72.00 °C. @ 25.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure:2.234000 mmHg @ 25.00 °C. (est)
Vapor Density:3.31 ( Air = 1 )
Flash Point: 137.00 °F. TCC ( 58.33 °C. )
logP (o/w): 0.410
Shelf Life: 12.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
alcohol
water, 7.70E+04 mg/L @ 25 °C (exp)

Cosmetic Information:

Suppliers:

Advanced Biotech
FURFURAL NATURAL
98% min.
Advanced Biotech
FURFURAL SYNTHETIC
96% min.
Allan Chemical
Furfural
Artiste
Furfural Natural
Aurochemicals
FURFURAL, Natural
Beijing Lys Chemicals
Fufural
Berjé
Furfural Natural
Media
Charkit Chemical
FURFURAL REDISTILLED (FURALDEHYDE, 2-) FEMA 2489
Charkit Chemical
FURFURAL REDISTILLED (FURFURALDEHYDE) F0050 2489
Charkit Chemical
FURFURAL
CJ Latta & Associates
FURFURAL
EMD Millipore
For experimental / research use only.
Furfural
Ernesto Ventós
FURFURAL NATURAL
Fleurchem
furfural natural
Frutarom
FURFURAL
KOSHER
Flavor: Almond, Caramellic, Sweet, Woody
CBD Offering
Glentham Life Sciences
Furfural
H. Interdonati, Inc.
Furfural Natural, Kosher
Featured Products
IFF
FURFURAL
KOSHER
Flavor: Almond, Caramellic, Sweet, Woody
Indukern F&F
FURFURAL NATURAL
Odor: SWEET, BREADY
Indukern F&F
FURFURAL
Odor: SWEET, BREADY
Inoue Perfumery
FURFURAL
Lluch Essence
FURFURALDEHYDE NATURAL
Lluch Essence
FURFURALDEHYDE
M&U International
NAT. FURFURAL
M&U International
2-FURALDEHYDE, Kosher
Moellhausen
FURFURAL
Odor: fresh, aromatic, bitter almond note
Flavor: sweet caramel-like, nutty, baked bread, almond
Penta International
FURFURAL FCC GRADE
Penta International
FURFURAL NATURAL
Penta International
FURFURAL REFINED
Perfumery Laboratory
Furfural
Odor: Sweet, almond, woody with a pronounced note of fragrant bread
R C Treatt & Co Ltd
Furfural
Reincke & Fichtner
Furfural natural
Reincke & Fichtner
Furfural
Santa Cruz Biotechnology
For experimental / research use only.
Furfural 98%
Sigma-Aldrich
Furfural, ≥98%, FCC, FG
Odor: almond; woody; sweet
Certified Food Grade Products
Sigma-Aldrich
Furfural, natural, ≥98%, FCC, FG
Odor: almond; woody; sweet
SRS Aromatics
FURFURALDEHYDE
Taytonn ASCC
Furfural (Furfuraldehyde) Redist
Odor: Almond, Caramellic/ Caramel, Sweet, Woody
TCI AMERICA
For experimental / research use only.
Furfural >98.0%(GC)
Tengzhou Xiang Yuan Aroma Chemicals
Furfural
United International
Furfural
Vigon International
Furfural Natural
WEN International
FURFURAL Natural
WholeChem
Fufural

Safety Information:

Preferred SDS: View
European information :
Most important hazard(s):
T - Toxic.
R 21 - Harmful in contact with skin.
R 23 - Toxic by inhalation.
R 25 - Toxic if swallowed.
R 36/37 - Irritating to eyes and respiratory system.
R 40 - Limited evidence of a carcinogenic effect.
S 02 - Keep out of the reach of children.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
gavage-rat LD50 [sex: M,F] M:145 - 204 F:90 - 119 mg/kg
(Brown, 1982)

oral-rat LD50 65 mg/kg
Bromatologia i Chemia Toksykologiczna. Vol. 13, Pg. 371, 1980.

oral-mouse LD50 400 mg/kg
Biochemical Journal. Vol. 34, Pg. 1196, 1940.

intravenous-mouse LD50 152 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

intraperitoneal-mouse LD50 102 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

oral-guinea pig LD50 541 mg/kg
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"BLOOD: HEMORRHAGE
Hygiene and Sanitation Vol. 32(5), Pg. 158, 1967.

oral-rabbit LD50 7031 mg/kg
Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.

intraperitoneal-rat LD50 1200 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 743, 1978.

oral-dog LD50 950 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLDGASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: ATAXIA
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 279, 1969.

intravenous-dog LD50 250 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

parenteral-frog LDLo 23000 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 21, Pg. 65, 1923.

intravenous-mouse LD50 152 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

oral-rabbit LDLo 800 mg/kg
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYELUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Pharmacology and Experimental Therapeutics. Vol. 21, Pg. 65, 1923.

Dermal Toxicity:
skin-rabbit LD50 620 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

subcutaneous-rat LD50 148 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 279, 1969.

subcutaneous-mouse LD50 119 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

subcutaneous-dog LD50 214 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

subcutaneous-guinea pig LDLo 100 mg/kg
Food and Cosmetics Toxicology. Vol. 16, Pg. 759, 1978.

subcutaneous-rabbit LDLo 500 mg/kg
Hygiene and Sanitation Vol. 32(5), Pg. 158, 1967.

Inhalation Toxicity:
inhalation-rat LC50 175 ppm/6H
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
American Industrial Hygiene Association Journal. Vol. 50, Pg. A359, 1989.

inhalation-dog LC50 370 ppm/6H
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 279, 1969.

inhalation-human TCLo 310 ug/m3
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 26(6), Pg. 3, 1961.

inhalation-mouse TCLo 370 ppm/6H
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 279, 1969.

Safety in Use Information:

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect:
Carcinogenicity
View the IFRA Standard
View IFRA Standards Library for complete information.
Please review Amendment 49 IFRA documentation for complete information.
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%):
Category 1: Products applied to the lips
0.0010 %
Category 2: Products applied to the axillae
0.0010 %
Category 3: Products applied to the face/body using fingertips
0.0010 %
Category 4: Products related to fine fragrance
0.0010 %
Category 5: Products applied to the face and body using the hands (palms), primarily leave-on
Category 5A: Body lotion products applied to the body using the hands (palms), primarily leave-on
0.0010 %
Category 5B: Face moisturizer products applied to the face using the hands (palms), primarily leave-on
0.0010 %
Category 5C: Hand cream products applied to the hands using the hands (palms), primarily leave-on
0.0010 %
Category 5D: Baby Creams, baby Oils and baby talc
0.0010 %
Category 6: Products with oral and lip exposure
0.0010 %
Category 7: Products applied to the hair with some hand contact
Category 7A: Rinse-off products applied to the hair with some hand contact
0.0010 %
Category 7B: Leave-on products applied to the hair with some hand contact
0.0010 %
Category 8: Products with significant anogenital exposure
0.0010 %
Category 9: Products with body and hand exposure, primarily rinse off
0.0010 %
Category 10: Household care products with mostly hand contact
Category 10A: Household care excluding aerosol products (excluding aerosol/spray products)
0.0010 %
Category 10B: Household aerosol/spray products
0.0010 %
Category 11: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate
Category 11A: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
0.0010 %
Category 11B: Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
0.0010 %
Category 12: Products not intended for direct skin contact, minimal or insignificant transfer to skin
0.050
Notes:
IFRA FLAVOR REQUIREMENTS:

Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.

Maximised Survey-derived Daily Intakes (MSDI-EU): 440.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA): 460.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 9700 (μg/person/day)
Threshold of Concern:540 (μg/person/day)
Structure Class: II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
average usual ppmaverage maximum ppm
baked goods: -17.00000
beverages(nonalcoholic): -4.00000
beverages(alcoholic): -10.00000
breakfast cereal: --
cheese: --
chewing gum: -45.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -13.00000
fruit ices: -13.00000
gelatins / puddings: -0.80000
granulated sugar: --
gravies: --
hard candy: -12.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 25.0000060.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): --
Edible ices, including sherbet and sorbet (03.0): 25.0000050.00000
Processed fruit (04.1): -0.25000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): -0.25000
Confectionery (05.0): 25.00000700.00000
Chewing gum (05.3): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 5.0000025.00000
Bakery wares (07.0): 5.0000025.00000
Meat and meat products, including poultry and game (08.0): --
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): --
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 25.0000063.00000
Foodstuffs intended for particular nutritional uses (13.0): 25.00000-
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 15.0000028.00000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 17.0000030.00000
Ready-to-eat savouries (15.0): -25.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): -25.00000

Safety References:

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to Furfural and Furfural Diethylacetal.
View page or View pdf

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 13 (FGE.13); Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14 (Commission Regulation (EC) No 1565/2000 of 18
View page or View pdf

Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Flavouring Group Evaluation 66 (FGE.66)[1]:Consideration of furfuryl alcohol and related flavouring substances evaluated by JECFA (55th meeting) structurally related to Furfuryl and furan derivatives with and without additional side chain substituents and heteroatoms evaluated by EFSA in FGE.13 (2005)
View page or View pdf

Flavouring Group Evaluation 218: alpha,beta-Unsaturated aldehydes and precursors from subgroup 4.2 of FGE.19: Furfural derivatives - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 13Rev1: Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf

Consideration of sulfur-substituted furan derivatives used as flavouring agents evaluated by JECFA (59th meeting) structurally related to a subgroup of substances within the group of �Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14� evaluated by EFSA in FGE.13Rev1 (2009)
View page or View pdf

Flavouring Group Evaluation 67 (FGE.67): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 218, Revision 1 (FGE.218Rev1): alpha,beta-Unsaturated aldehydes and precursors from subgroup 4.2 of FGE.19: Furfural derivatives.
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 13, Revision 2 (FGE.13Rev2): Furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 66, Revision 1 (FGE.66Rev1): Consideration of Furfuryl Alcohol and Related Flavouring Substances Evaluated by JECFA (55th meeting)
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 67, Revision 1 (FGE.67Rev.1): Consideration of 40 furan-substituted aliphatic hydrocarbons, alcohols, aldehydes, ketones, carboxylic acids and related esters, sulfides, disulfides and ethers evaluated by JECFA at the 65th meeting (JECFA, 2006b) and re-evaluated at the 69th meeting (JECFA, 2009c)
View page or View pdf

Safety and efficacy of furfuryl and furan derivatives belonging to chemical group 14 when used as flavourings for all animal species and categories
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 13 Revision 3 (FGE.13Rev3): furfuryl and furan derivatives with and without additional side-chain substituents and heteroatoms from chemical group 14
View page or View pdf

EPI System: View
EPA-Iris:IRIS
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):98-01-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :7362
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WISER:UN 1199
WGK Germany:2
furan-2-carbaldehyde
Chemidplus:0000098011
EPA/NOAA CAMEO:hazardous materials
RTECS:98-01-1

References:

furan-2-carbaldehyde
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:98-01-1
Pubchem (cid):7362
Pubchem (sid):134970962
Flavornet:98-01-1
Pherobase:View

Other Information:

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
UM BBD:Search
KEGG (GenomeNet):C14279
HMDB (The Human Metabolome Database):HMDB32914
FooDB:FDB010897
YMDB (Yeast Metabolome Database):YMDB01459
Export Tariff Code:2932.12.0000
Typical G.C.
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
Formulations/Preparations:
•grade: technical, refined.•natural, synthetic, industrial, 98% grades

Potential Blenders and core components :

For Odor
bready
coffee furanone
FL/FR
buttery
3,4-
hexane dione
FL/FR
caramellic
2-oxo
butyric acid
FL/FR
cyclotene
FL/FR
diethyl malate
FL/FR
maltol
FL/FR
maltyl propionate
FL/FR
menthone lactone
FL/FR
5-
methyl furfural
FL/FR
shoyu furanone
FL/FR
strawberry furanone acetate
FL/FR
toffee furanone
FL/FR
coffee
coffee fragrance
FR
earthy
octyl phenyl acetate
FL/FR
fermented
valeraldehyde
FL/FR
floral
coranol (Firmenich)
FR
dihydrolinalool
FL/FR
3,6-
dimethyl-3-octanol
FL/FR
ethyl linalool
FR
ethyl linalyl acetal
FR
ethyl linalyl acetate
FR
ethyl linalyl ether
FL/FR
ho leaf oil
FR
ho wood oil
FR
laevo-
linalool
FL/FR
dextro-
linalool
FL/FR
linalool
FL/FR
linalool oxide
FL/FR
linalyl anthranilate
FL/FR
ortho-
methyl acetophenone
FL/FR
orris rhizome absolute (iris germanica)
FL/FR
orris rhizome absolute (iris pallida)
FL/FR
tetrahydrolinalool
FL/FR
fruity
bread thiophene
FL/FR
methyl nonane dione
FL/FR
3-
methyl-2-butenal
FL/FR
pineapple hydroxyhexanoate
FL/FR
tetrahydrofurfuryl acetate
FL/FR
herbal
lovage tincture
FL/FR
minty
dextro-
carvone
FL/FR
musty
2-
acetyl pyrrole
FL/FR
nutty
3,5-
cocoa pyrazine
FL/FR
filbert pyrazine
FL/FR
2,6-
lutidine
FL/FR
phenolic
ethyl vanillate
FL/FR
popcorn
2-
acetyl pyrazine
FL/FR
2-
acetyl pyridine
FL/FR
spicy
caraway seed oleoresin
FL/FR
cubeb oil
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
methyl heptadienone
FL/FR
sulfurous
benzothiazole
FL/FR
tobacco
methyl benzoxole
FL/FR
woody
juniper berry oleoresin
FL/FR
pinacol
FR
For Flavor
No flavor group found for these
2-
acetyl-3,4,5,6-tetrahydropyridine
FL
diethyl malate
FL/FR
ethyl linalyl ether
FL/FR
dextro-
linalool
FL/FR
menthone lactone
FL/FR
4-
methoxybenzoyl oxyacetic acid
FL
2-
methoxythiazole
FL
methyl nonane dione
FL/FR
octyl phenyl acetate
FL/FR
anisic
anisic
ortho-
methyl acetophenone
FL/FR
bready
2-
propionyl thiazole
FL
brown
2-oxo
butyric acid
FL/FR
5-
methyl furfural
FL/FR
tetrahydrofurfuryl acetate
FL/FR
burnt
furfuryl alcohol
FL
buttery
3,4-
hexane dione
FL/FR
caramellic
butterscotch praline flavor
FL
caramel dione
FL
caramel nut cream flavor
FL
caramel nut fudge flavor
FL
cyclotene
FL/FR
maltol
FL/FR
maltyl propionate
FL/FR
maple nut flavor
FL
pyruvaldehyde
FL
shoyu furanone
FL/FR
strawberry furanone acetate
FL/FR
toffee furanone
FL/FR
chocolate
chocolate caramel nut flavor
FL
citrus
linalool
FL/FR
laevo-
linalool
FL/FR
cocoa
butyraldehyde
FL
coffee
coffee distillates
FL
coffee enhancers
FL
diisoamyl thiomalate
FL
2-
thiophene thiol
FL
corn
2-
acetyl pyridine
FL/FR
2-
acetyl-2-thiazoline
FL
creamy
ethyl vanillate
FL/FR
floral
dihydrolinalool
FL/FR
linalyl anthranilate
FL/FR
orris flavor
FL
tetrahydrolinalool
FL/FR
fruity
acetyl isovaleryl
FL
banana nut bread flavor
FL
banana walnut bread flavor
FL
bread thiophene
FL/FR
(E,E)-
methyl sorbate
FL
3-
methyl-2-butenal
FL/FR
pineapple hydroxyhexanoate
FL/FR
green
linalool oxide
FL/FR
methyl heptadienone
FL/FR
herbal
3,6-
dimethyl-3-octanol
FL/FR
lovage tincture
FL/FR
malty
malt flavor
FL
meaty
benzothiazole
FL/FR
metallic
2,5-
dihydroxy-1,4-dithiane
FL
minty
dextro-
carvone
FL/FR
musty
2-
ethoxythiazole
FL
nutty
2-
acetyl pyrrole
FL/FR
3,5-
cocoa pyrazine
FL/FR
coffee furanone
FL/FR
filbert pyrazine
FL/FR
2,6-
lutidine
FL/FR
methyl benzoxole
FL/FR
peanut brittle flavor
FL
peanut oxazole
FL
roasted
2-
acetyl pyrazine
FL/FR
spicy
caraway seed oleoresin
FL/FR
cubeb oil
FL/FR
alpha-
methyl cinnamaldehyde
FL/FR
sulfurous
2-
naphthyl mercaptan
FL
sweet
agave flavor
FL
orris rhizome absolute (iris germanica)
FL/FR
orris rhizome absolute (iris pallida)
FL/FR
waxy
furfuryl octanoate
FL
winey
valeraldehyde
FL/FR
woody
juniper berry oleoresin
FL/FR

Occurrence (nature, food, other):

allspice plant
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amyris wood oil @ <0.10%
Data GC Search Trop Picture
anise seed
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apple fruit
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apricot fruit
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basil plant
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bread white bread
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cacao bean
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cacao exocarp
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calamus
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caraway seed
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cassia plant
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chamomile sweet false chamomile plant
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cherry morello cherry
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cichorium intybus l. root extract @ 2.80%
Data GC Search Trop Picture
cinnamon ceylon cinnamon bark
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cinnamon ceylon cinnamon root bark
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clove bud
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clove fruit
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clove plant
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coffee arabica coffee bean
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coffee bean
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coriander fruit
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coriander seed
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corn plant
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corn shoot
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cornmint plant
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cranberry fruit
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dill plant
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eschweilera coriacea (a. p. dc.) mori flower oil brazil @ 1.00%
Data GC Search Trop Picture
ginger rhizome oil
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grapefruit
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guava fruit
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hyssop shoot
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kohlrabi stem
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lavender oil spike spain @ 9.485%
Data GC Search Trop Picture
lemon balm tissue culture
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lemongrass plant
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lime fruit
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lovage root
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malpighia glabra l. fruit oil @ 56.80%
Data GC Search Trop Picture
malt
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mango sap
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mastic fruit oil @ 0.04%
Data GC Search Trop Picture
mustard white mustard
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nutmeg seed
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oat hull husk
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orange fruit
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osmanthus absolute @ trace%
Data GC Search Trop Picture
pimento leaf
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plum fruit
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potato chip
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potato plant
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pumpkin
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raspberry red raspberry fruit
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rice cakes
PbMd Search PMC Picture
rice petiole
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roselle calyx
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rugula herb
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rum
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spearmint oil
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tamarind fruit oil
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tamarind seed oil
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tea black tea
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tomato fruit
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tricholoma matsutake
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vanilla
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water mint leaf
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whiskey malt whiskey
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Synonyms:

2-formyl furan
formylfuran
2-furaldehyde
2-furan aldehyde
2-furan carbonal
2-furan carboxaldehyde
furan-2-carbaldehyde
furan-2-carboxaldehyde
2-furanaldehyde
2-furancarbonal
2-furancarboxaldehyde
2-furfural
furfural (furfuraldehyde) redist
furfural (natural)
furfural crude
furfural natural
furfural synthetic
furfural-refined flavor grade
furfuraldehyde
2-furfuraldehyde
a-furfuraldehyde
alpha-furfuraldehyde
furfuryl aldehyde
a-furole
2-furyl aldehyde
2-furyl carboxaldehyde
2-furyl methanal
2-furylcarboxaldehyde
2-furylmethanal
pyromucic aldehyde

Articles:

Info:Volatile Flavor Components in Bogyojosaeng and Suhong Cultivars of Strawberry (Fragaria ananassa Duch.)
PubMed:Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose.
PubMed:Effect of roasting conditions on color and volatile profile including HMF level in sweet almonds (Prunus dulcis).
PubMed:Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans).
PubMed:Diacetyl levels and volatile profiles of commercial starter distillates and selected dairy foods.
PubMed:Physicochemical and flavor characteristics of flavoring agent from mungbean protein hydrolyzed by bromelain.
PubMed:Hot and cold water infusion aroma profiles of Hibiscus sabdariffa: fresh compared with dried.
PubMed:Key aroma components of a dry-cured sausage with high fat content (sobrassada).
PubMed:Honey collected from different floras of Chandigarh Tricity: a comparative study involving physicochemical parameters and biochemical activities.
PubMed:Proton transfer reaction time-of-flight mass spectrometry monitoring of the evolution of volatile compounds during lactic acid fermentation of milk.
PubMed:Chemical and biochemical study of industrially produced San Simón da Costa smoked semi-hard cow's milk cheeses: Effects of storage under vacuum and different modified atmospheres.
PubMed:Study on the role of precursors in coffee flavor formation using in-bean experiments.
PubMed:Role of roasting conditions in the profile of volatile flavor chemicals formed from coffee beans.
PubMed:Prediction of sensory properties of Brazilian Arabica roasted coffees by headspace solid phase microextraction-gas chromatography and partial least squares.
PubMed:Impact of forced-aging process on madeira wine flavor.
PubMed:The chemical characterization of the aroma of dessert and sparkling white wines (Pedro Ximénez, Fino, Sauternes, and Cava) by gas chromatography-olfactometry and chemical quantitative analysis.
PubMed:Determination of volatile flavor components in danggui cultivars by solvent free injection and hydrodistillation followed by gas chromatographic-mass spectrometric analysis.
PubMed:Physicochemical model to interpret the kinetics of aroma extraction during wine aging in wood. Model limitations suggest the necessary existence of biochemical processes.
PubMed:Reduction of stale flavor development in low-heat skim milk powder via epicatechin addition.
PubMed:Inhibition of key aroma compound generated during ultrahigh-temperature processing of bovine milk via epicatechin addition.
PubMed:3-Hydroxy-4,5-dimethyl-2(5H)-furanone levels in fortified Madeira wines: relationship to sugar content.
PubMed:Influence of the brewing process on furfuryl ethyl ether formation during beer aging.
PubMed:Evolution of chemical and sensory properties during aging of top-fermented beer.
PubMed:3-Hydroxy-4,5-dimethyl-2(5H)-furanone: a key odorant of the typical aroma of oxidative aged Port wine.
PubMed:Thresholds of carcinogenicity of flavors.
PubMed:Furfural-cysteine model reaction in food grade nonionic oil/water microemulsions for selective flavor formation.
PubMed:Generation of Maillard compounds from inulin during the thermal processing of Agave tequilana Weber Var. azul.
PubMed:Volatile flavor constituents of acerola (Malpighia emarginata DC.) fruit.
PubMed:Quantitative gas chromatography-olfactometry carried out at different dilutions of an extract. Key differences in the odor profiles of four high-quality Spanish aged red wines.
PubMed:Structured fluids as microreactors for flavor formation by the Maillard reaction.
PubMed:Volatile flavor components of rice cakes.
PubMed:The FEMA GRAS assessment of furfural used as a flavour ingredient. Flavor and Extract Manufacturers' Association.
PubMed:[The quantitative composition of natural and technologically changed aromas of plants. IV. Enzymic and thermal reaction products formed during the processing of tomatoes (author's transl)].
PubMed:[Flavor enhancement in rye bread by pre-baking].
PubMed:[Shortened dough preparation of wheat bread and its effect on the flavor. 1. Carbonyl compounds and ethanol].
PubMed:Microbial Lipid Production from Corn Stover via Mortierella isabellina.
PubMed:Content and evolution of potential furfural compounds in commercial milk-based infant formula powder after opening the packet.
PubMed:Investigation of α-Dicarbonyl Compounds in Baby Foods by High-Performance Liquid Chromatography Coupled with Electrospray Ionization Mass Spectrometry.
PubMed:Bamboo: A new source of carbohydrate for biorefinery.
PubMed:Conversion of xylose into furfural using lignosulfonic Acid as catalyst in ionic liquid.
PubMed:Modified Method Combining in Situ Detoxification with Simultaneous Saccharification and Cofermentation (SSCF) as a Single Step for Converting Exploded Rice Straw into Ethanol.
PubMed:Nutritional and physicochemical characteristic of commercial Spanish citrus juices.
PubMed:Some qualitative properties of different monofloral honeys.
PubMed:Physico-chemical and sensory changes during the storage of lal peda.
PubMed:Wheat bran biorefinery: an investigation on the starch derived glucose extraction accompanied by pre- and post-treatment steps.
PubMed:Aroma enhancement and enzymolysis regulation of grape wine using β-glycosidase.
PubMed:5-hydroxymethyl-2-furfural and derivatives formed during acid hydrolysis of conjugated and bound phenolics in plant foods and the effects on phenolic content and antioxidant capacity.
PubMed:Industrial robust yeast isolates with great potential for fermentation of lignocellulosic biomass.
PubMed:Sequential extrusion-ozone pretreatment of switchgrass and big bluestem.
PubMed:Semi-continuous anaerobic co-digestion of cow manure and steam-exploded Salix with recirculation of liquid digestate.
PubMed:Validation of a HPLC method for determination of hydroxymethylfurfural in crude palm oil.
PubMed:Tolerance of S. cerevisiae and Z. mobilis to inhibitors produced during dilute acid hydrolysis of soybean meal.
PubMed:Characterisation of volatile compounds in a smoke flavouring from rice husk.
PubMed:Physicochemical parameters and sensory properties of honeys from Buenos Aires region.
PubMed:Kinetics of browning, phenolics, and 5-hydroxymethylfurfural in commercial sparkling wines.
PubMed:Evaluating the composition and processing potential of novel sources of Brazilian biomass for sustainable biorenewables production.
PubMed:Toxicological assessment of enzyme-treated asparagus extract in rat acute and subchronic oral toxicity studies and genotoxicity tests.
PubMed:Sequential extrusion-microwave pretreatment of switchgrass and big bluestem.
PubMed:Synthesis of the Insecticide Prothrin and Its Analogues from Biomass-Derived 5-(Chloromethyl)furfural.
PubMed:Characterization of aroma compounds of Chinese famous liquors by gas chromatography-mass spectrometry and flash GC electronic-nose.
PubMed:Production and purification of xylooligosaccharides from oil palm empty fruit bunch fibre by a non-isothermal process.
PubMed:Hydroxymethylfurfural: a possible emergent cause of honey bee mortality?
PubMed:In vitro antioxidant and antiproliferative activities of 5-hydroxymethylfurfural.
PubMed:Comparison of an HPTLC method with the Reflectoquant assay for rapid determination of 5-hydroxymethylfurfural in honey.
PubMed:Application of a high-throughput process analytical technology metabolomics pipeline to Port wine forced ageing process.
PubMed:New approaches to determination of HMF.
PubMed:Developing an effective means to reduce 5-hydroxymethyl-2-furfural from caramel colour.
PubMed:Simultaneous analysis of furfural metabolites from Rehmanniae radix preparata by HPLC-DAD-ESI-MS.
PubMed:Isolation, structural elucidation, and biological evaluation of a 5-hydroxymethyl-2-furfural derivative, asfural, from enzyme-treated asparagus extract.
PubMed:Impacts of selected dietary polyphenols on caramelization in model systems.
PubMed:Physicochemical properties of the Harenna forest honey, Bale, Ethiopia.
PubMed:Identification of 5-hydroxymethyl-2-furfural (5-HMF) in Cava sparkling wines by LC-DAD-MS/MS and NMR spectrometry.
PubMed:Study of hydroxymethylfurfural and furfural formation in cakes during baking in different ovens, using a validated multiple-stage extraction-based analytical method.
PubMed:Pretreatment and fractionation of wheat straw using various ionic liquids.
PubMed:The decay of ascorbic acid in a model wine system at low oxygen concentration.
PubMed:Buckwheat honeys: screening of composition and properties.
PubMed:Detection of extraction artifacts in the analysis of honey volatiles using comprehensive two-dimensional gas chromatography.
PubMed:Wheat bran biorefinery--a detailed investigation on hydrothermal and enzymatic treatment.
PubMed:Preliminary studies of bio-oil from fast pyrolysis of coconut fibers.
PubMed:Changes of antioxidant activity and formation of 5-hydroxymethylfurfural in honey during thermal and microwave processing.
PubMed:Impact of flavour solvent (propylene glycol or triacetin) on vanillin, 5-(hydroxymethyl)furfural, 2,4-decadienal, 2,4-heptadienal, structural parameters and sensory perception of shortcake biscuits over accelerated shelf life testing.
PubMed:Identification of bitter compounds in whole wheat bread.
PubMed:Identification of volatile compounds from a food-grade vinegar attractive to house flies (Diptera: Muscidae).
PubMed:Indirect competitive ELISA based on monoclonal antibody for the detection of 5-hydroxymethyl-2-furfural in milk, compared with HPLC.
PubMed:Effect of concentration temperature on some bioactive compounds and antioxidant proprieties of date syrup.
PubMed:Port wine oxidation management: a multiparametric kinetic approach.
PubMed:Effects of extrusion, infrared and microwave processing on Maillard reaction products and phenolic compounds in soybean.
PubMed:Industrially applicable strategies for mitigating acrylamide, furan, and 5-hydroxymethylfurfural in food.
PubMed:Effect of 5-hydroxymethylfurfural derived from processed Cornus officinalis on the prevention of high glucose-induced oxidative stress in human umbilical vein endothelial cells and its mechanism.
PubMed:Congeners in sugar cane spirits aged in casks of different woods.
PubMed:Rapid determination of 5-hydroxymethylfurfural by DART ionization with time-of-flight mass spectrometry.
PubMed:Short communication: possible mechanism for inhibiting the formation of polymers originated from 5-hydroxymethyl-2-furaldehyde by sulfite groups in the dairy thermal process.
PubMed:Jujube honey from China: physicochemical characteristics and mineral contents.
PubMed:Utilization of acetic acid-rich pyrolytic bio-oil by microalga Chlamydomonas reinhardtii: reducing bio-oil toxicity and enhancing algal toxicity tolerance.
PubMed:An efficient method for the determination of furan derivatives in apple cider and wine by solid phase extraction and high performance liquid chromatography--diode array detector.
PubMed:Physicochemical and antioxidant properties of Malaysian honeys produced by Apis cerana, Apis dorsata and Apis mellifera.
PubMed:Reactivity of thermally treated α-dicarbonyl compounds.
PubMed:Untangling the chemistry of port wine aging with the use of GC-FID, multivariate statistics, and network reconstruction.
PubMed:Volatile profiling of high quality hazelnuts (Corylus avellana L.): chemical indices of roasting.
PubMed:Determination of metabolites of 5-hydroxymethylfurfural in human urine after oral application.
PubMed:Impact of cooking and handling conditions on furanic compounds in breaded fish products.
PubMed:Effect of adulteration versus storage on volatiles in unifloral honeys from different floral sources and locations.
PubMed:Influence of the industrial processing and the floral origin into the volatile constituents of honeybee-collected pollen.
PubMed:Contribution of ALDH1A1 isozyme to detoxification of aldehydes present in food products.
PubMed:Influence of processing on the volatile profile of strawberry spreads made with isomaltulose.
PubMed:Dry vs soaked wood: modulating the volatile extractible fraction of oak wood by heat treatments.
PubMed:A comparison of different dilute solution explosions pretreatment for conversion of distillers' grains into ethanol.
PubMed:Characterisation of tequila according to their major volatile composition using multilayer perceptron neural networks.
PubMed:Characterisation of commercial aromatised vinegars: phenolic compounds, volatile composition and antioxidant activity.
PubMed:Controlling the Maillard reaction by reactant encapsulation: sodium chloride in cookies.
PubMed:Reporter gene mutation in the livers of gpt delta mice treated with 5-(hydroxymethyl)-2-furfural, a contaminant of various foods.
PubMed:Okara promoted acrylamide and carboxymethyl-lysine formation in bakery products.
PubMed:Simultaneous determination of iridoid glycosides, phenethylalcohol glycosides and furfural derivatives in Rehmanniae Radix by high performance liquid chromatography coupled with triple-quadrupole mass spectrometry.
PubMed:Sensomics analysis of taste compounds in balsamic vinegar and discovery of 5-acetoxymethyl-2-furaldehyde as a novel sweet taste modulator.
PubMed:Short communication: simultaneous analysis of reducing sugars and 5-hydroxymethyl-2-furaldehyde at a low concentration by high performance anion exchange chromatography with electrochemical detector, compared with HPLC with refractive index detector.
PubMed:Identification and mode of action of 5-hydroxymethyl-2-furfural (5-hmf) and 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) as potent xanthine oxidase inhibitors in vinegars.
PubMed:Quantification of furanic compounds in coated deep-fried products simulating normal preparation and consumption: optimisation of HS-SPME analytical conditions by response surface methodology.
PubMed:Application of selected ion flow tube mass spectrometry coupled with chemometrics to study the effect of location and botanical origin on volatile profile of unifloral American honeys.
PubMed:Impact of steam explosion on biogas production from rape straw in relation to changes in chemical composition.
PubMed:Development and validation of an HPLC method to determine metabolites of 5-hydroxymethylfurfural (5-HMF).
PubMed:The potential for oligosaccharide production from the hemicellulose fraction of biomasses through pretreatment processes: xylooligosaccharides (XOS), arabinooligosaccharides (AOS), and mannooligosaccharides (MOS).
PubMed:Micellar electrokinetic chromatography method for the simultaneous determination of furanic compounds in honey and vegetable oils.
PubMed:In depth study of acrylamide formation in coffee during roasting: role of sucrose decomposition and lipid oxidation.
PubMed:Determination of very low levels of 5-(hydroxymethyl)-2-furaldehyde (HMF) in natural honey: comparison between the HPLC technique and the spectrophotometric white method.
PubMed:1,2-dicarbonyl compounds in commonly consumed foods.
PubMed:In vivo detoxification of furfural during lipid production by the oleaginous yeast Trichosporon fermentans.
PubMed:Mutagenicity of 5-hydroxymethylfurfural in V79 cells expressing human SULT1A1: identification and mass spectrometric quantification of DNA adducts formed.
PubMed:On-fiber furan formation from volatile precursors: a critical example of artefact formation during Solid-Phase Microextraction.
PubMed:Effect of maturity stage and storage on flavor compounds and sensory description of berrycactus (Myrtillocactus geometrizans).
PubMed:Survey of 1,2-dicarbonyl compounds in commercial honey of different floral origin.
PubMed:Discrimination of Chinese vinegars based on headspace solid-phase microextraction-gas chromatography mass spectrometry of volatile compounds and multivariate analysis.
PubMed:Effect of temperature and some added compounds on the stability of blood orange marmalade.
PubMed:Kinetics of 3-deoxy-D-erythro-hexos-2-ulose in unifloral honeys.
PubMed:Diacetyl levels and volatile profiles of commercial starter distillates and selected dairy foods.
PubMed:Demonstration of antioxidant and anti-inflammatory bioactivities from sugar-amino acid maillard reaction products.
PubMed:Study of 5-hydroxymethylfurfural and its metabolite 5-sulfooxymethylfurfural on induction of colonic aberrant crypt foci in wild-type mice and transgenic mice expressing human sulfotransferases 1A1 and 1A2.
PubMed:Optimization of furfural and 5-hydroxymethylfurfural production from wheat straw by a microwave-assisted process.
PubMed:Changes in the initial stages of a glucose-proline Maillard reaction model system influences dairy product quality during thermal processing.
PubMed:Nematicidal activity of (E,E)-2,4-decadienal and (E)-2-decenal from Ailanthus altissima against Meloidogyne javanica.
PubMed:Simultaneous quantitation of 2-acetyl-4-tetrahydroxybutylimidazole, 2- and 4-methylimidazoles, and 5-hydroxymethylfurfural in beverages by ultrahigh-performance liquid chromatography-tandem mass spectrometry.
PubMed:Hydrothermal pretreatment of sugarcane bagasse using response surface methodology improves digestibility and ethanol production by SSF.
PubMed:The potential of biodetoxification activity as a probiotic property of Lactobacillus reuteri.
PubMed:Degradation of 5-hydroxymethylfurfural during yeast fermentation.
PubMed:Maillard reaction and protein cross-linking in relation to the solubility of milk powders.
PubMed:Intestinal carcinogenesis of two food processing contaminants, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 5-hydroxymethylfurfural, in transgenic FVB min mice expressing human sulfotransferases.
PubMed:Effect of pretreatment severity on the conversion of barley straw to fermentable substrates and the release of inhibitory compounds.
PubMed:Development of an enzyme-linked immunosorbent assay for the determination of 5-hydroxymethyl-2-furfural in food.
PubMed:Determination of low-molecular mass phenols in red wines: the influence of chips, staves and micro-oxygenation aging tank.
PubMed:Biological pretreatment with a cellobiose dehydrogenase-deficient strain of Trametes versicolor enhances the biofuel potential of canola straw.
PubMed:Rapid analysis of formic acid, acetic acid, and furfural in pretreated wheat straw hydrolysates and ethanol in a bioethanol fermentation using atmospheric pressure chemical ionisation mass spectrometry.
PubMed:Preparation and characterization of a molecularly imprinted polymer by grafting on silica supports: a selective sorbent for patulin toxin.
PubMed:Mead production: tradition versus modernity.
PubMed:Therm
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