dimeticone

antifoaming agents, anticaking agents

2D:
3D:
CAS Number:	9006-65-9
FDA UNII:	5L1VVC3K8O
Category:	antifoaming agents, anticaking agents
IUPAC Name:	dimeticone
InChI :	InChI=1/C8H24O2Si3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h1-8H3
Std.InChI:	InChI=1S/C8H24O2Si3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h1-8H3
InChIKey :	CXQXSVUQTKDNFP-UHFFFAOYAT
Std.InChIKey:	CXQXSVUQTKDNFP-UHFFFAOYSA-N
SMILES :	C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C
Molar Refractivity :	68.75 ± 0.3 cm3 (est)
Parachor :	567.2 ± 4.0 cm3 (est)
Index of Refraction :	1.404 ± 0.02 (est)
Surface Tension :	16.7 ± 3.0 dyne/cm (est)
Density :	0.843 ± 0.06 g/cm3 (est)
Polarizability :	27.25 ± 0.5 10-24cm3 (est)

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
JECFA Food Additive:	Polydimethylsiloxane
GSFA Codex:	Polydimethylsiloxane (900a)
DG SANTE Food Additives:	dimethyl polysiloxane

Physical Properties:

Appearance:	colorless clear viscous liquid (est)
Assay:	80.00 to 100.00
Food Chemicals Codex Listed:	No
Boiling Point:	153.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:	4.359000 mmHg @ 25.00 °C. (est)
Flash Point:	131.00 °F. TCC ( 55.00 °C. ) (est)
logP (o/w):	3.646 (est)
Soluble in:
	aliphatic hydrocarbons
	aromatic hydrocarbons
	water, 5.428e-007 mg/L @ 25 °C (est)
Insoluble in:
	alcohol
	water

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	antifoaming agents skin conditioning skin conditioning - emollient skin protecting agents

Suppliers:

BOC Sciences

For experimental / research use only.

Dimethicone

Odor: characteristic

Use: A silicone oil consisting of a mixture of fully methylated linear siloxane polymers end-blocking with trimethylsilox

Santa Cruz Biotechnology

For experimental / research use only.

Dimeticone

Sigma-Aldrich

For experimental / research use only.

Dimeticone European Pharmacopoeia (EP) Reference Standard

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 > 20000 mg/kg Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
antifoaming agents, anticaking agents
Recommendation for dimeticone usage levels up to:
	not for fragrance use.

Recommendation for dimeticone flavor usage levels up to:
	not for flavor use.

Safety References:

European Food Safety Authority (EFSA) reference(s):

Re-evaluation of dimethyl polysiloxane (E 900) as a food additive
View page or View pdf

EPI System: View

ClinicalTrials.gov:search

Daily Med:search

Chemical Carcinogenesis Research Information System:Search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :24705

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

dimethyl-bis(trimethylsilyloxy)silane

Chemidplus:0009006659

References:

	dimethyl-bis(trimethylsilyloxy)silane
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	24705
Pubchem (sid):	135024877

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
KEGG (GenomeNet):	C07261
HMDB (The Human Metabolome Database):	Search
FDA Listing of Food Additive Status:	View
ChemSpider:	View
Wikipedia:	View
Formulations/Preparations: a typical antiperspirant stick formula is: 27.5 wt % stearic acid monoethanolamide; 24.0 wt % poly(dimethylsiloxane) (low viscosity, volatile); 20.0 wt % rehydrol powder; 15.0 wt % propoxylated myristyl alcohol; 9.0 wt % propylene glycol; 3.0 wt % distilled or deionized water; 1.0 wt % perfume; and 0.5 wt % myristyl lactate.

Potential Blenders and core components :

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):

not found in nature

Synonyms:

	dimethyl polysiloxane
	dimethyl polysiloxane, bis(trimethylsilyl)-terminated
	dimethyl-bis(trimethylsilyloxy)silane
	dimeticonum
	octamethyltrisiloxane
	PDMS
	pentamethyl(trimethylsilyloxy)disiloxane
	polysilane
	trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-

Articles:

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CONTENTS

EU/US Properties EU/US Suppliers Safety Safety in use Safety reference References Other Blenders Uses Occurrence Synonyms Articles