| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 84-66-2 |
| ECHA EC Number: | 201-550-6 |
| FDA UNII: | UF064M00AF |
| Category: | solvents/deluents for cosmetic and fragrance agents |
| IUPAC Name: | diethyl phthalate |
| InChI : | InChI=1/C12H14O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-8H,3-4H2,1-2H3 |
| Std.InChI: | InChI=1S/C12H14O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-8H,3-4H2,1-2H3 |
| InChIKey : | FLKPEMZONWLCSK-UHFFFAOYAV |
| Std.InChIKey: | FLKPEMZONWLCSK-UHFFFAOYSA-N |
| SMILES : | CCOC(=O)C1=CC=CC=C1C(=O)OCC |
| MDL: | MFCD00009111 |
| Molar Refractivity : | 59.06 ± 0.3 cm3 (est) |
| Parachor : | 496.5 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.507 ± 0.02 (est) |
| Surface Tension : | 39.3 ± 3.0 dyne/cm (est) |
| Density : | 1.121 ± 0.06 g/cm3 (est) |
| Polarizability : | 23.41 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA Mainterm (IAUFC): | 84-66-2 ; DIETHYL PHTHALATE |
| FDA Regulation: | |
| FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.105 Adhesives. | |
| Appearance: | colorless clear liquid (est) |
| Assay: | 98.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.11500 to 1.11800 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 9.278 to 9.303 |
| Refractive Index: | 1.49900 to 1.50300 @ 20.00 °C. |
| Melting Point: | -3.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 172.00 °C. @ 12.00 mm Hg |
| Boiling Point: | 298.00 to 299.00 °C. @ 760.00 mm Hg |
| Acid Value: | 1.00 max. KOH/g |
| Vapor Pressure: | 0.002100 mmHg @ 25.00 °C. |
| Vapor Density: | 7.7 ( Air = 1 ) |
| Flash Point: | 320.00 °F. TCC ( 160.00 °C. ) |
| logP (o/w): | 2.420 |
| Soluble in: | |
| alcohol | |
| water, 1080 mg/L @ 25 °C (exp) | |
| Insoluble in: | |
| paraffin oil | |
| Stability: | |
| non-discoloring in most media | |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xn - Harmful. | |
| R 36/37/38 - Irritating to eyes, respiratory system, and skin. R 63 - Possible risk of harm to the unborn child. S 02 - Keep out of the reach of children. S 23 - Do not breath vapour. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Human Experience: | |
| 100 %: no irritation or sensitization. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 8600 mg/kg BEHAVIORAL: WITHDRAWALBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 25, 1980. intraperitoneal-rat LD50 5058 ul/kg Journal of Pharmaceutical Sciences. Vol. 61, Pg. 51, 1972. oral-rabbit LD50 1000 mg/kg "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1904, 1963. oral-mouse LD50 6172 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 17(11), Pg. 51, 1973. intraperitoneal-mouse LD50 2749 mg/kg LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMAKIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"BLOOD: CHANGES IN SPLEEN Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947. oral-guinea pig LD50 8600 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: WITHDRAWAL Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 25, 1980. | |
| Dermal Toxicity: | |
| subcutaneous-guinea pig LD50 3000 mg/kg "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1904, 1963. | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| solvents/deluents for cosmetic and fragrance agents | |||
| Recommendation for diethyl phthalate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for diethyl phthalate flavor usage levels up to: | |||
| not for flavor use. | |||
| European Food Safety Authority (EFSA) reference(s): |
| Statement on the re-classification of some phthalates for consistency with the new SCF guidelines for food contact materials by the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) View page or View pdf |
| EPI System: View |
| EPA-Iris:IRIS |
| NIOSH International Chemical Safety Cards:search |
| NIOSH Pocket Guide:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):84-66-2 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :6781 |
| National Institute of Allergy and Infectious Diseases:Data |
| SCCNFP:opinion |
| WGK Germany:2 |
| diethyl benzene-1,2-dicarboxylate |
| Chemidplus:000084662 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:84-66-2 |
| diethyl benzene-1,2-dicarboxylate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 84-66-2 |
| Pubchem (cid): | 6781 |
| Pubchem (sid): | 134972334 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C14175 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2917.39.4000 |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •grade: technical•grade of purity: technical: 99+ % | |
| None Found |
| not found in nature |
| anozol | |
| 1,2- | benzene dicarboxylic acid diethyl ester |
| ortho- | benzene dicarboxylic acid diethyl ester |
| benzene-1,2-dicarboxylic acid diethyl ester | |
| 1,2- | benzenedicarboxylic acid diethyl ester |
| o- | benzenedicarboxylic acid diethyl ester |
| benzenedicarboxylic acid, diethyl ester | |
| 1,2- | benzenedicarboxylic acid, diethyl ester |
| di ethyl phthalate | |
| diethyl 1,2-benzene dicarboxylate | |
| diethyl 1,2-benzenedicarboxylate | |
| diethyl benzene-1,2-dicarboxylate | |
| diethyl ester of phthalic acid | |
| diethyl o-phenylene diacetate | |
| diethyl o-phthalate | |
| diethyl ortho-phenylene diacetate | |
| diethyl ortho-phthalate | |
| diethyl phthalate N.F. | |
| diethyl phthalate odorless | |
| diethylphthalate | |
| dpx-f5384 | |
| ortho-bis( | ethoxycarbonyl) benzene |
| o-bis( | ethoxycarbonyl)benzene |
| ethyl 2-(ethoxycarbonyl)benzoate | |
| neantine | |
| palatinol A | |
| phthalic acid diethyl ester | |
| phthalic acid, diethyl ester | |
| phthalol | |
| placidol E | |
| solvanol | |
| unimoll DA | |
| uniplex 105 |
