| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 75-18-3 |
| ECHA EC Number: | 200-846-2 |
| FDA UNII: | QS3J7O7L3U |
| CoE Number: | 483 |
| Category: | flavor and fragrance agents |
| IUPAC Name: | dimethyl sulfide |
| InChI : | InChI=1/C2H6S/c1-3-2/h1-2H3 |
| Std.InChI: | InChI=1S/C2H6S/c1-3-2/h1-2H3 |
| InChIKey : | QMMFVYPAHWMCMS-UHFFFAOYAH |
| Std.InChIKey: | QMMFVYPAHWMCMS-UHFFFAOYSA-N |
| SMILES : | CSC |
| MDL: | MFCD00008562 |
| Molar Refractivity : | 19.31 ± 0.3 cm3 (est) |
| Parachor : | 162.3 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.425 ± 0.02 (est) |
| Surface Tension : | 21.3 ± 3.0 dyne/cm (est) |
| Density : | 0.822 ± 0.06 g/cm3 (est) |
| Polarizability : | 7.65 ± 0.5 10-24cm3 (est) |
| Fragrance Demo Formulas | |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 452 methyl sulfide |
| DG SANTE Food Flavourings: | 12.006 dimethyl sulfide |
| FEMA Number: | 2746 methyl sulfide |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 75-18-3 ; METHYL SULFIDE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants. | |
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 99.00 to 100.00 |
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 0.84200 to 0.84700 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 7.006 to 7.048 |
| Specific Gravity: | 0.84000 to 0.85000 @ 20.00 °C. |
| Pounds per Gallon - est.: | 6.998 to 7.081 |
| Refractive Index: | 1.43100 to 1.44100 @ 20.00 °C. |
| Melting Point: | -98.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 37.30 °C. @ 760.00 mm Hg |
| Boiling Point: | -37.50 to -37.30 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 646.973022 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 2.1 ( Air = 1 ) |
| Flash Point: | -34.00 °F. TCC ( -36.67 °C. ) |
| logP (o/w): | 0.977 (est) |
| Shelf Life: | 12.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: | |
| alcohol | |
| dipropylene glycol | |
| ethyl ether | |
| water, 2.249e+004 mg/L @ 25 °C (est) | |
| water, 2.20E+04 mg/L @ 25 °C (exp) | |
| Insoluble in: | |
| water | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | perfuming agents |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xn - Harmful. | |
| R 11 - Highly flammable. R 22 - Harmful if swallowed. R 37/38 - Irritating to respiratory system and skin. R 41 - Risk of serious damage to eyes. S 02 - Keep out of the reach of children. S 07 - Keep container tightly closed. S 09 - Keep container in a well-ventilated place. S 16 - Keep away from sources of ignition - No Smoking. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 29 - Do not empty into drains. S 33 - Take precautionary measures against static discharge. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| gavage-rat LD50 3300 mg/kg (Koptyaev, 1967b) gavage-mouse LD50 3700 mg/kg (Koptyaev, 1967b) intraperitoneal-mouse LD50 8000 mg/kg International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. Vol. 3, Pg. 41, 1961. oral-rat LD50 3300 mg/kg BEHAVIORAL: IRRITABILITYBEHAVIORAL: GENERAL ANESTHETICBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 32(3), Pg. 3, 1967. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 365, 1979. | |
| Inhalation Toxicity: | |
| inhalation-rat LC50 40250 ppm KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASEDGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Personal Communication from H.B. Lackey, Chemical Products Div., Crown Zellerbach, Camas, WA 98607, June 9, 1978Vol. 09JUN1978 inhalation-mouse LC50 31620 ug/m3 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 16(6), Pg. 46, 1972. | |
| Category: | |||
| flavor and fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 380.00 (μg/capita/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | - | 1.60000 | |
| beverages(nonalcoholic): | - | 1.10000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 0.30000 | |
| fruit ices: | - | 0.30000 | |
| gelatins / puddings: | - | 0.13000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | - | 1.40000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf |
| Flavouring Group Evaluation 8, Revision 1 (FGE.08Rev1): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| Flavouring Group Evaluation 08 Rev2 (FGE.08 Rev2): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 8, Revision 3 (FGE.08Rev3): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 08, Revision 4 (FGE.08Rev4): Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical groups 20 and 30 View page or View pdf |
| Scientific Opinion on the safety and efficacy of aliphatic and aromatic mono- and di-thiols and mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups (chemical group 20) when used as flavourings for all animal species View page or View pdf |
| Outcome of the consultation with Member States and EFSA on the basic substance application for approval of dimethyl sulfide to be used in plant protection as a non-lethal food attractant for truffle beetle View page or View pdf |
| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):75-18-3 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :1068 |
| National Institute of Allergy and Infectious Diseases:Data |
| WISER:UN 1164 |
| WGK Germany:1 |
| methylsulfanylmethane |
| Chemidplus:0000075183 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:75-18-3 |
| methylsulfanylmethane | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 75-18-3 |
| Pubchem (cid): | 1068 |
| Pubchem (sid): | 134970746 |
| Flavornet: | 75-18-3 |
| Pherobase: | View |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00580 |
| HMDB (The Human Metabolome Database): | HMDB02303 |
| FooDB: | FDB003591 |
| YMDB (Yeast Metabolome Database): | YMDB01674 |
| Export Tariff Code: | 2930.90.5050 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| FAO: | Methyl sulfide |
| Formulations/Preparations: •grades or purity: 99.8%•exact-s | |
| dimethyl monosulfide | |
| dimethyl sulfide 5% in ethyl acetate natural | |
| dimethyl sulfide 5% in ETOH natural | |
| dimethyl sulfide natural | |
| dimethyl sulphide | |
| dimethyl sulphide A grade | |
| dimethyl sulphide B grade | |
| dimethyl sulphyde | |
| dimethyl thioether | |
| dimethylsulphide | |
| DMS 10% in dipropylene glycol | |
| exact-S | |
| methane thiomethane | |
| methane, 1,1'-thiobis- | |
| methyl monosulfide | |
| methyl sulfide | |
| methyl sulphide 'A plus' | |
| methyl sulphide 'A' grade | |
| methyl sulphide technical | |
| methyl thioether | |
| ( | methylsulfanyl)methane |
| methylsulfanylmethane | |
| 2- | thiapropane |
| thiobis(methane) | |
| thiobismethane | |
| 2- | thiopropane |
