| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 69-65-8 |
| ECHA EC Number: | 200-711-8 |
| FDA UNII: | 3OWL53L36A |
| Category: | sweeteners, humectants, texturizers, stabilizers, bulking agents |
| IUPAC Name: | dextro-mannitol |
| InChI : | InChI=1/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1 |
| Std.InChI: | InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1 |
| InChIKey : | FBPFZTCFMRRESA-KVTDHHQDBH |
| Std.InChIKey: | FBPFZTCFMRRESA-KVTDHHQDSA-N |
| SMILES : | C([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O |
| MDL: | MFCD00064287 |
| Molar Refractivity : | 38.89 ± 0.3 cm3 (est) |
| Parachor : | 360.7 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.597 ± 0.02 (est) |
| Surface Tension : | 99.8 ± 3.0 dyne/cm (est) |
| Density : | 1.596 ± 0.06 g/cm3 (est) |
| Polarizability : | 15.41 ± 0.5 10-24cm3 (est) |
| Appearance: | white crystalline powder (est) |
| Assay: | 96.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 164.00 to 168.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 290.00 to 295.00 °C. @ 760.00 mm Hg |
| Flash Point: | 558.00 °F. TCC ( 292.50 °C. ) (est) |
| logP (o/w): | -3.262 (est) |
| Soluble in: | |
| acetic acid, slightly | |
| ethyl alcohol, vary slightly | |
| water, 216000 mg/L @ 25 °C (exp) | |
| Insoluble in: | |
| ether | |
| Anhui Haibei |
| Mannito |
| BOC Sciences |
| For experimental / research use only. |
| D-Mannitol |
| Carbosynth |
| For experimental / research use only. |
| D-Mannitol |
| Cargill, Inc. |
| Mannidex® mannitol Flavor: characteristic Mannitol polyol sugar substitutes have very low hygroscopicity, provides bulk, texture and preservative benefits of sucrose in sugar-free and calorie-reduced products. Mannitol is suitable for dental health, weight management and sugar avoiders. Mannitol also has a cooling effect in the mouth. |
| Charkit Chemical |
| MANNITOL ACS |
| ECSA Chemicals |
| D-MANNITOL RPE-FOR ANALYSIS, G 250 |
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| ECSA Chemicals |
| MANNITOL PH.EUR.(C*Pharm Mannidex 16700) |
| EMD Millipore |
| For experimental / research use only. |
| D(-)-Mannitol |
| Farbest-Tallman Foods |
| Mannitol |
| Foodchem International |
| Mannitol |
| George Uhe Company |
| D-Mannitol |
| Glentham Life Sciences |
| D-Mannitol, EP, USP grade |
| Glentham Life Sciences |
| D-Mannitol |
| Indis NV |
| For experimental / research use only. |
| Mannitol |
| Kao Corporation |
| MANNITOL KAO (JP GRADE) Odor: characteristic Use: Sweetener: Masking agent for medicines giving cool and fresh sweetness, low calorie content sweetener. |
| Kraft Chemical |
| Mannitol |
| O'Laughlin Industries |
| MANNITOL |
| Penta International |
| MANNITOL GRANULAR USP |
| Penta International |
| MANNITOL POWDER USP |
| Pfanstiehl, Inc |
| D-Mannitol, High Purity Low Endotoxin USP, EP, JP, ChP Odor: characteristic Use: Mannitol is classified as a sugar alcohol and is derived from a sugar (mannose) by reduction. Other widely known polyols are xylitol and sorbitol. Mannitol and sorbitol are isomers, differing only in the orientation of the hydroxyl group on carbon two. The physical properties of mannitol make it suitable for use as a bulking agent in tableting. However, it also has unique chemical properties that enable it to stabilize a wide variety of pharmaceutical preparations, including liquid formulations, as well as protect proteins from denaturation/degradation upon lyophilization, spray drying, and reconstitution. |
| Prinova |
| Mannitol |
| Qingdao Dacon Trading |
| Mannitol Powder |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| D(-)Mannitol ≥98% |
| Sigma-Aldrich |
| For experimental / research use only. |
| D-Mannitol meets EP, FCC, USP testing specifications |
| Sinofi Food Ingredients |
| Mannitol Flavor: characteristic Sugar Substitutes, Chewing Gum, Confections, Spirit Drinks, Dried Fruit and Vegetables, Alcoholic Beverages, Texturizer, Humectant, Flavoring Agent, Lubricant, Release Agent, Bulking Agent, Anticaking Agent, Firming Agent. |
| TCI AMERICA |
| For experimental / research use only. |
| D-Mannitol >99.0%(T) |
| United International |
| Mannitol Nat. |
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 13500 mg/kg Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. intravenous-rat LD50 9690 mg/kg Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. oral-mouse LD50 22000 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE FAO Nutrition Meetings Report Series. Vol. 40, Pg. 160, 1967. intravenous-mouse LD50 7470 mg/kg Yakkyoku. Pharmacy. Vol. 32, Pg. 1367, 1981. intraperitoneal-mouse LD50 14000 mg/kg Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 98, 1936. intravenous-man TDLo 17143 mg/kg/2D VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTIONGASTROINTESTINAL: NAUSEA OR VOMITINGKIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Archives of Internal Medicine. Vol. 144, Pg. 2053, 1984. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| sweeteners, humectants, texturizers, stabilizers, bulking agents | |||
| Recommendation for dextro-mannitol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dextro-mannitol flavor usage levels up to: | |||
| not for flavor use. | |||
| European Food Safety Authority (EFSA) reference(s): |
| Outcome of the public consultation on a draft protocol for assessing exposure to sweeteners as part of their safety assessment under the food additives re-evaluation programme View page or View pdf |
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):69-65-8 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :6251 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol |
| Chemidplus:0000069658 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:OP2060000 for cas# 69-65-8 |
| (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 69-65-8 |
| Pubchem (cid): | 6251 |
| Pubchem (sid): | 134971672 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| KEGG (GenomeNet): | C00392 |
| HMDB (The Human Metabolome Database): | HMDB00765 |
| FooDB: | FDB001982 |
| YMDB (Yeast Metabolome Database): | YMDB00830 |
| Export Tariff Code: | 2905.43.0000 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| None Found |
| binder in adhesives | |
| FL | flavor enhancers |
| humectants |
| anise root Search Trop Picture | |
| barley root Search Trop Picture | |
| bay laurel root Search Trop Picture | |
| buckthorn sea buckthorn fruit Search Trop Picture | |
| caraway Search Trop Picture | |
| celery leaf Search Trop Picture | |
| celery plant Search Trop Picture | |
| celery root Search Trop Picture | |
| celery shoot Search Trop Picture | |
| celery stem Search Trop Picture | |
| cherry sour cherry fruit Search Trop Picture | |
| chicory plant Search Trop Picture | |
| cinnamon ceylon cinnamon plant Search Trop Picture | |
| coriander fruit Search Trop Picture | |
| cumin seed Search Trop Picture | |
| dandelion root Search Trop Picture | |
| leek wild leek plant Search Trop Picture | |
| lettuce plant Search Trop Picture | |
| not found in nature | |
| olive leaf Search Trop Picture | |
| onion bulb Search Trop Picture | |
| pomegranate leaf Search Trop Picture | |
| pomegranate pericarp Search Trop Picture | |
| pomegranate root Search Trop Picture | |
| pomegranate seed Search Trop Picture | |
| pomegranate stem Search Trop Picture | |
| pomegranate stem bark Search Trop Picture | |
| pomegranate twig Search Trop Picture | |
| raspberry red raspberry fruit Search Trop Picture |
| cordycepic acid | |
| cosmospheres GYAM-M | |
| diosmol | |
| (2R,3R,4R,5R)- | hexan-1,2,3,4,5,6-hexol |
| (2R,3R,4R,5R)- | hexane-1,2,3,4,5,6-hexol |
| (2R,3R,4R,5R)-1,2,3,4,5,6- | hexanehexol |
| invenex | |
| isotol | |
| maniton S | |
| maniton-s | |
| manna sugar | |
| mannazucker | |
| mannidex | |
| mannigen | |
| mannisol | |
| mannistol | |
| mannit | |
| D- | mannit |
| mannit p | |
| D- | mannitol |
| D(-)- | mannitol |
| mannitol granular USP | |
| mannitol powder USP | |
| mannogem 2080 | |
| marine crystal | |
| mushroom sugar | |
| osmitrol | |
| osmofundin | |
| osmosal | |
| resectisol | |
| rightsweet mannitol |
