ethyl vanillin propylene glycol acetal

flavor and fragrance agents

2D:
3D:
CAS Number:	68527-76-4
ECHA EC Number:	271-281-7
FDA UNII:	PP1L5D6A0Y
Category:	flavor and fragrance agents
IUPAC Name:	ethyl vanillin propylene glycol acetal
InChI :	InChI=1/C12H16O4/c1-3-14-11-6-9(4-5-10(11)13)12-15-7-8(2)16-12/h4-6,8,12-13H,3,7H2,1-2H3
Std.InChI:	InChI=1S/C12H16O4/c1-3-14-11-6-9(4-5-10(11)13)12-15-7-8(2)16-12/h4-6,8,12-13H,3,7H2,1-2H3
InChIKey :	IFUIILQWHYHIEK-UHFFFAOYAF
Std.InChIKey:	IFUIILQWHYHIEK-UHFFFAOYSA-N
SMILES :	CCOC1=C(C=CC(=C1)C2OCC(O2)C)O
MDL:	MFCD00036667
Molar Refractivity :	59.39 ± 0.3 cm3 (est)
Parachor :	493.5 ± 4.0 cm3 (est)
Index of Refraction :	1.524 ± 0.02 (est)
Surface Tension :	41.9 ± 3.0 dyne/cm (est)
Density :	1.156 ± 0.06 g/cm3 (est)
Polarizability :	23.54 ± 0.5 10-24cm3 (est)

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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JECFA Food Flavoring:	954 ethyl vanillin propylene glycol acetal
FEMA Number:	3838 ethyl vanillin propylene glycol acetal
FDA:	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):	68527-76-4 ; ETHYL VANILLIN PROPYLENE GLYCOL ACETAL

Physical Properties:

Appearance:	pale yellow to yellow viscous liquid (est)
Assay:	99.00 to 100.00 sum of isomers
Food Chemicals Codex Listed:	No
Specific Gravity:	1.15800 to 1.16800 @ 25.00 °C.
Pounds per Gallon - (est).:	9.636 to 9.719
Refractive Index:	1.52600 to 1.53600 @ 20.00 °C.
Boiling Point:	160.00 °C. @ 1.00 mm Hg
Boiling Point:	346.00 to 347.00 °C. @ 760.00 mm Hg
Vapor Pressure:	0.000020 mmHg @ 25.00 °C. (est)
Flash Point:	230.00 °F. TCC ( 110.00 °C. )
logP (o/w):	1.779 (est)
Soluble in:
	alcohol
	water, 1460 mg/L @ 25 °C (est)
Insoluble in:
	water
Stability:
	alkali
Similar Items:note
acetoin propylene glycol acetal
anisaldehyde propylene glycol acetal
benzaldehyde propylene glycol acetal
butyraldehyde propylene glycol acetal
isobutyraldehyde propylene glycol acetal
cinnamaldehyde propylene glycol acetal
citral propylene glycol acetal
cyclamen aldehyde propylene glycol acetal
decanal propylene glycol acetal
furfural propylene glycol acetal
heliotropyl propylene glycol acetal
hexanal propylene glycol acetal
(E)-2-hexen-1-al propylene glycol acetal
hydroxycitronellal propylene glycol acetal
melon heptenal propylene glycol acetal
6-methyl-5-hepten-2-one propylene glycol acetal
nonanal propylene glycol acetal
2-nonanone propylene glycol acetal
octanal propylene glycol acetal
perillaldehyde propylene glycol acetal
phenyl acetaldehyde propylene glycol acetal
para-tolualdehyde propylene glycol acetal
undecanal propylene glycol acetal
valeraldehyde propylene glycol acetal
isovaleraldehyde propylene glycol acetal
vanillin propylene glycol acetal

Organoleptic Properties:

sweet vanilla creamy spicy sweet sharp vanilla creamy spicy clove sweet creamy vanilla sweet

Cosmetic Information:

None found

Suppliers:

Apple Flavor & Fragrance

Ethyl Vanillin PG Acetal

Bedoukian Research

ETHYL VANILLIN PROPYLENE GLYCOL ACETAL

sds

≥98.0% (sum of isomers), Kosher

Odor: A vanilla odor with a spicy, clove like undertone

Use: Used as a replacement for Ethyl Vanillin; stable in alkali, little discoloration.

Flavor: Smokey, not creamy-guaiacol

Adds smoky, vanilla notes to a variety of flavors, especially milk chocolate.

Beijing Lys Chemicals

Ethylvanillin Propylene Glycol Acetal

BOC Sciences

For experimental / research use only.

ETHYL VANILLIN PROPYLENE GLYCOL ACETAL 98.0% (sum of isomers)

Carbosynth

For experimental / research use only.

Ethyl Vanillin Propylene Glycol Acetal

DeLong Chemicals America

3-Ethoxy-4-hydroxybenzaldehyde-propylene glycol acetal

Inoue Perfumery

ETHYL VANILLIN PG ACETAL

Jiangyin Healthway

Ethyl Vanillin Propylene Glycol Acetal

New functional food ingredients

Lluch Essence

ETHYL VANILLIN PROPYLENE GLYCOL ACETAL

Penta International

ETHYL VANILLIN PROPYLENE GLYCOL ACETAL

Tengzhou Xiang Yuan Aroma Chemicals

Ethyl vanillin p.g.a

Tianjin Danjun International

Ethyl vanillin propylene glycol acetal

United International

Ethyl Vanillin Propyleneglycol Acetal

Vigon International

Ethyl Vanillin P.G. Acetal

Safety Information:

Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 36 - Wear suitable protective clothing.

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Recommendation for ethyl vanillin propylene glycol acetal usage levels up to:
	5.0000 % in the fragrance concentrate.

Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 18
Click here to view publication 18
		average usual ppm	average maximum ppm
baked goods:		55.00000	121.00000
beverages(nonalcoholic):		23.00000	39.00000
beverages(alcoholic):		7.00000	13.00000
breakfast cereal:		351.00000	429.00000
cheese:		-	-
chewing gum:		49.00000	49.00000
condiments / relishes:		17.00000	17.00000
confectionery froastings:		125.00000	352.00000
egg products:		-	-
fats / oils:		0.08000	0.20000
fish products:		-	-
frozen dairy:		16.00000	35.00000
fruit ices:		-	-
gelatins / puddings:		24.00000	52.00000
granulated sugar:		-	-
gravies:		-	-
hard candy:		21.00000	39.00000
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		5.00000	5.00000
milk products:		1817.00000	1824.00000
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		74.00000	116.00000
soups:		-	-
sugar substitutes:		-	-
sweet sauces:		133.00000	224.00000

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):68527-76-4

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :109457

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

2-ethoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol

Chemidplus:0068527764

References:

	2-ethoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	109457
Pubchem (sid):	135066803

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	HMDB36203
FooDB:	FDB015061
Export Tariff Code:	2911.00.5000
ChemSpider:	View

Potential Blenders and core components :

For Odor

No odor group found for these

bird of paradise fragrance
FR

aldehydic

acetyl nonyryl
FL/FR

anisic

para-

acetanisole
FL/FR

ortho-

anisaldehyde
FL/FR

para-

anisaldehyde
FL/FR

methyl para-anisate
FL/FR

balsamic

benzoin
FL/FR

siam

benzoin absolute
FL/FR

sumatra

benzoin absolute
FL/FR

benzoin absolute replacer
FL/FR

sumatra

benzoin gum
FL/FR

siam

benzoin resin
FL/FR

sumatra

benzoin resin
FL/FR

siam

benzoin resin oil
FR

benzoin resin replacer
FR

sumatra

benzoin resinoid
FL/FR

siam

benzoin resinoid
FL/FR

benzoin resinoid replacer
FR

benzoyl acetone
FL/FR

guaiacyl phenyl acetate
FL/FR

opoponax absolute (commiphora erythraea var. glabrescens engle)
FL/FR

opoponax absolute replacer
FR

oriental fragrance
FR

oriental specialty
FR

peru balsam absolute
FL/FR

peru balsam oil
FL/FR

peru balsam replacer
FR

peru balsam resinoid
FL/FR

peru balsam resinoid replacer
FR

peru balsam specialty
FR

berry

raspberry ketone methyl ether
FL/FR

buttery

acetoin
FL/FR

acetyl butyryl
FL/FR

acetyl isobutyryl
FL/FR

acetyl propionyl
FL/FR

butyl butyryl lactate
FL/FR

caramellic

2-oxo

butyric acid
FL/FR

levulinic acid
FL/FR

strawberry furanone acetate
FL/FR

cheesy

butyric acid
FL/FR

chemical

styralyl alcohol
FL/FR

chocolate

chocolate fragrance
FR

chocolate specialty
FR

vanillyl ethyl ether
FL/FR

citrus

bergamot vanilla specialty
FR

coconut

alpha-

angelica lactone
FL/FR

coconut decanone methyl
FR

delta-

decalactone
FL/FR

delta-2-

dodecenolactone
FL/FR

delta-

nonalactone
FL/FR

delta-

octalactone
FL/FR

gamma-

octalactone
FL/FR

delta-

undecalactone
FL/FR

coumarinic

coumane
FL/FR

creamy

gamma-

butyrolactone
FL/FR

creamy lactone
FL/FR

geranyl ethyl acetal
FR

heptyl dihydro-5-methyl-2(3H)-furanone
FL/FR

para-

vanillic acid
FL/FR

para-

vanillyl alcohol
FL/FR

veratraldehyde
FL/FR

earthy

nonen-3-ol
FL/FR

fatty

(Z)-

dairy lactone
FL/FR

ethyl undecylenate
FL/FR

methyl octanoic acid
FL/FR

fermented

butyl laevo-lactate
FL/FR

valeraldehyde
FL/FR

floral

acetophenone
FL/FR

angel dust fragrance
FR

benzyl phenyl acetate
FL/FR

coffee flower absolute
FR

para-

cresyl laurate
FL/FR

hawthorn fragrance
FR

hawthorn specialty
FR

heliotrope fragrance
FR

heliotrope specialty
FR

heliotropin
FL/FR

longoza absolute replacer
FR

para-

methyl acetophenone
FL/FR

beta-

naphthyl methyl ketone
FL/FR

fruity

acetoin acetate
FL/FR

para-

anisyl methyl ketone
FL/FR

para-

anisyl propionate
FL/FR

blackberry vanilla fragrance
FR

gamma-

decalactone
FL/FR

1,2-

dimethyl butyl 2-butenoate
FR

ethyl methyl-para-tolyl glycidate
FL/FR

farnesyl acetone
FL/FR

guaiacyl propionate
FL/FR

methyl (Z)-5-octenoate
FL/FR

octyl butyrate
FL/FR

tolualdehydes (mixed o,m,p)
FL/FR

(R)-delta-

undecalactone
FL/FR

gamma-

undecalactone (aldehyde C-14 (so-called))
FL/FR

vanilla carboxylate
FL/FR

green

iso

butyl benzyl carbinol
FL/FR

butyl lactate
FL/FR

(Z)-4-

hepten-1-ol
FL/FR

(Z)-4-

heptenal
FL/FR

(Z)-4-

heptenal diethyl acetal
FL/FR

hay

new mown hay fragrance
FR

milky

laevo-

glutamine
CS

minty

menthoxypropane diol
FL/FR

mushroom

octen-2-ol
FL/FR

musk

ethylene brassylate
FL/FR

omega-

pentadecalactone
FL/FR

naphthyl

2,4-

dimethyl benzaldehyde
FL/FR

para-

methyl anisole
FL/FR

nutty

nutty cyclohexenone
FL/FR

resorcinol
FR

2,3,5,6-

tetramethyl pyrazine
FL/FR

phenolic

ethyl vanillate
FL/FR

ortho-

guaiacol
FL/FR

powdery

para-

anisyl acetate
FL/FR

para-

anisyl alcohol
FL/FR

smoky

2,6-

dimethoxyphenol
FL/FR

alpha-

ethoxy-ortho-cresol
FL/FR

spicy

para-

anisyl formate
FL/FR

(E)-

coconut decanone ethyl
FR

dianthus ethone
FR

ethyl guaiacol
FL/FR

3-(2-

furyl) acrolein
FL/FR

(E)-para-

methoxycinnamaldehyde
FL/FR

para-

methoxycinnamaldehyde
FL/FR

methyl guaiacol
FL/FR

spicy acetoacetate
FL/FR

zingerone
FL/FR

sweet

tonka bean absolute replacer
FR

vanilla bean absolute (vanilla spp.)
FL/FR

vanilla oleoresin bali
FL/FR

vanilla resinoid
FL/FR

vanilla tahitensis fruit extract
FL/FR

tonka

amyl-alpha-pyrone
FL/FR

coumarin
FR

gamma-

hexalactone
FL/FR

mint lactone
FL/FR

octahydrocoumarin
FL/FR

tropical

curcuma amada roxb. rhizome oil CO2 extract
FL/FR

vanilla

acetovanillone
FL/FR

crème brulee fragrance
FR

ortho-

dimethyl hydroquinone
FL/FR

ethyl vanillin
FL/FR

ethyl vanillin acetate
FR

ethyl vanillin diethyl acetal
FR

ethyl vanillin hexylene glycol acetal
FR

ethyl vanillin isobutyrate
FL/FR

heliotropyl alcohol
FL/FR

methyl vanillate
FL/FR

propenyl guaethol
FL/FR

vanilla
FR

vanilla aromatica fruit extract
FL/FR

vanilla bean absolute (vanilla planifolia)
FL/FR

vanilla bean absolute CO2 extract (vanilla planifolia)
FL/FR

vanilla bean fragrance
FR

vanilla bean oil (vanilla planifolia)
FR

vanilla bean oil (vanilla tahitensis)
FL/FR

vanilla bean oil CO2 extract
FL/FR

vanilla bean tincture
FR

vanilla cresol
FR

vanilla extract
FL/FR

french

vanilla fragrance
FR

country

vanilla fragrance
FR

vanilla oleoresin bourbon
FL/FR

vanilla planifolia fruit extract
FL/FR

vanilla planifolia fruit infusion
FR

vanilla planifolia fruit water
FL/FR

vanilla specialty
FR

vanilla tahitensis fruit absolute
FR

vanilla tahitensis fruit absolute CO2 extract
FL/FR

vanilla tahitensis fruit oil CO2 extract
FR

vanillin
FL/FR

vanillin 2,3-butylene glycol acetal
FL/FR

vanillin hexylene glycol acetal
FR

vanillin propylene glycol acetal
FL/FR

vanillyl acetate
FL/FR

vanillyl butyl ether
FL/FR

vanillyl isobutyrate
FL/FR

vanillylidene acetone
FL/FR

vegetable

methional
FL/FR

waxy

allyl nonanoate
FL/FR

ethyl palmitate
FL/FR

methyl laurate
FL/FR

nonanoic acid
FL/FR

nonanol
FL/FR

octyl isobutyrate
FL/FR

delta-

tetradecalactone
FL/FR

undecanoic acid
FL/FR

woody

guaiacwood extract acetate
FR

guaiacyl acetate
FL/FR

hydroxybenzaldehyde
FL/FR

santalum paniculatum wood oil
FR

For Flavor

No flavor group found for these

allyl methyl trisulfide
FL

para-

anisyl propionate
FL/FR

benzoin
FL/FR

benzoyl acetone
FL/FR

coumane
FL/FR

decenoic acid
FL

ortho-

dimethyl hydroquinone
FL/FR

delta-2-

dodecenolactone
FL/FR

ethoxy-3-anisaldehyde
FL

alpha-

ethoxy-ortho-cresol
FL/FR

ethyl butyryl lactate
FL

farnesyl acetone
FL/FR

3-(2-

furyl) acrolein
FL/FR

glucoethyl vanillin
FL

glucovanillin
FL

guaiacyl propionate
FL/FR

heliotropyl alcohol
FL/FR

(E)-para-

methoxycinnamaldehyde
FL/FR

methoxysalicylaldehyde
FL

methyl para-anisate
FL/FR

methyl vanillate
FL/FR

(R)-delta-

undecalactone
FL/FR

vanillyl butyl ether
FL/FR

vanilmandelic acid
FL

acidic

levulinic acid
FL/FR

aldehydic

acetyl nonyryl
FL/FR

Potential Uses:

FL	chocolate cacao
FR	cream
FL	dairy
FL	marshmallow
FR	spice
FR	vanilla
FR	woody

Occurrence (nature, food, other):

not found in nature

Synonyms:

2-	ethoxy-4-(4-methyl-1,3-dioxolan-2-yl) phenol
2-	ethoxy-4-(4-methyl-1,3-dioxolan-2-yl)phenol
3-	ethoxy-4-hydroxybenzaldehyde-propylene glycol acetal
2-(3-	ethoxy4-hydroxyphenyl)-4-methyl-1,3-dioxolane
	ethyl vanillin PG acetal
	ethyl vanillin propylene glycol acetal 80-85%
	ethyl vanillin propyleneglycol acetal
	phenol, 2-ethoxy-4-(4-methyl-1,3-dioxolan-2-yl)-

Articles:

None found yet. Try the PubMed Search.

CONTENTS

EU/US Properties Organoleptic EU/US Suppliers Safety Safety in use Safety reference References Other Blenders Uses Occurrence Synonyms Articles