| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 646-06-0 |
| ECHA EC Number: | 211-463-5 |
| FDA UNII: | Y57RBG19JL |
| Category: | solvents |
| IUPAC Name: | dioxolane |
| InChI : | InChI=1/C3H6O2/c1-2-5-3-4-1/h1-3H2 |
| Std.InChI: | InChI=1S/C3H6O2/c1-2-5-3-4-1/h1-3H2 |
| InChIKey : | WNXJIVFYUVYPPR-UHFFFAOYAU |
| Std.InChIKey: | WNXJIVFYUVYPPR-UHFFFAOYSA-N |
| SMILES : | C1COCO1 |
| MDL: | MFCD00003207 |
| Molar Refractivity : | 17.04 ± 0.3 cm3 (est) |
| Parachor : | 169.3 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.396 ± 0.02 (est) |
| Surface Tension : | 32.7 ± 3.0 dyne/cm (est) |
| Density : | 1.046 ± 0.06 g/cm3 (est) |
| Polarizability : | 6.75 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| DG SANTE Food Contact Materials: | 1,3-dioxalane |
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.06000 @ 25.00 °C. |
| Melting Point: | -95.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 78.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 79.000000 mmHg @ 20.00 °C. |
| Vapor Density: | 2.6 ( Air = 1 ) |
| Flash Point: | 27.00 °F. TCC ( -2.78 °C. ) |
| logP (o/w): | -0.370 |
| Soluble in: | |
| alcohol | |
| ether | |
| water, 2.769e+005 mg/L @ 25 °C (est) | |
| water, 1.00E+06 mg/L @ 25 °C (exp) | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | solvents |
| Penta International |
| DIXOLANE |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 1,3-Dioxolane |
| Sigma-Aldrich |
| For experimental / research use only. |
| 1,3-Dioxolane ReagentPlus®, contains ∼75 ppm BHT as inhibitor, 99% |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 3000 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 60, 1949. oral-rabbit LD50 5200 mg/kg National Technical Information Service. Vol. OTS0537791 oral-mouse LD50 3200 mg/kg "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 70, 1982. intraperitoneal-rat LDLo 500 mg/kg GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"BEHAVIORAL: GENERAL ANESTHETICKIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED Journal of Pharmacy and Pharmacology. Vol. 11, Pg. 150, 1959. | |
| Dermal Toxicity: | |
| skin-rat LD50 15000 mg/kg National Technical Information Service. Vol. OTS0537791 skin-rabbit LD50 8480 ul/kg Union Carbide Data Sheet. Vol. 12/17/1971 | |
| Inhalation Toxicity: | |
| inhalation-rat LC50 20650 mg/m3/4H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 70, 1982. inhalation-mouse LC50 10500 mg/m3/2H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 70, 1982. inhalation-rabbit LCLo 32000 ppm/4H Union Carbide Data Sheet. Vol. 12/17/1971 | |
| Category: | |||
| solvents | |||
| Recommendation for dioxolane usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dioxolane flavor usage levels up to: | |||
| not for flavor use. | |||
| European Food Safety Authority (EFSA) reference(s): |
| Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to a 10th list of substances for food contact materials View page or View pdf |
| EPI System: View |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):646-06-0 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :12586 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| 1,3-dioxolane |
| Chemidplus:0000646060 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:JH6760000 for cas# 646-06-0 |
| 1,3-dioxolane | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 646-06-0 |
| Pubchem (cid): | 12586 |
| Pubchem (sid): | 134976960 |
| Pherobase: | View |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2932.90.5000 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| None Found |
| None Found |
| 1,3- | dioxalane |
| 1,3- | dioxolan |
| 1,3- | dioxolane |
| 1,3- | dioxole, dihydro- |
| ethylene glycol formal | |
| formal glycol |
| None found yet. Try the PubMed Search. |
