| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 637-64-9 |
| ECHA EC Number: | 211-296-8 |
| FDA UNII: | I1PIW4REZU |
| CoE Number: | 2069 |
| Category: | flavor and fragrance agents |
| IUPAC Name: | tetrahydrofurfuryl acetate |
| InChI : | InChI=1/C7H12O3/c1-6(8)10-5-7-3-2-4-9-7/h7H,2-5H2,1H3 |
| Std.InChI: | InChI=1S/C7H12O3/c1-6(8)10-5-7-3-2-4-9-7/h7H,2-5H2,1H3 |
| InChIKey : | AAQDYYFAFXGBFZ-UHFFFAOYAK |
| Std.InChIKey: | AAQDYYFAFXGBFZ-UHFFFAOYSA-N |
| SMILES : | CC(=O)OCC1CCCO1 |
| MDL: | MFCD00022478 |
| Molar Refractivity : | 35.78 ± 0.3 cm3 (est) |
| Parachor : | 333.4 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.434 ± 0.02 (est) |
| Surface Tension : | 34.7 ± 3.0 dyne/cm (est) |
| Density : | 1.049 ± 0.06 g/cm3 (est) |
| Polarizability : | 14.18 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 1442 tetrahydrofurfuryl acetate |
| DG SANTE Food Flavourings: | 13.166 tetrahydrofurfuryl acetate |
| FEMA Number: | 3055 tetrahydrofurfuryl acetate |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 637-64-9 ; TETRAHYDROFURFURYL ACETATE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart F--Flavoring Agents and Related Substances Sec. 172.515 Synthetic flavoring substances and adjuvants. | |
| Appearance: | colorless clear liquid (est) |
| Assay: | 97.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.05800 to 1.06400 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 8.804 to 8.854 |
| Refractive Index: | 1.43500 to 1.44000 @ 20.00 °C. |
| Boiling Point: | 194.00 to 195.00 °C. @ 753.00 mm Hg |
| Acid Value: | 4.00 max. KOH/g |
| Vapor Pressure: | 0.249000 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 4.9 ( Air = 1 ) |
| Flash Point: | 155.00 °F. TCC ( 68.33 °C. ) |
| logP (o/w): | 0.349 (est) |
| Soluble in: | |
| alcohol | |
| chloroform | |
| ethyl ether | |
| water, 1.384e+004 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | fragrance solvents |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
| R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 - Wear suitable gloves and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| flavor and fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for tetrahydrofurfuryl acetate usage levels up to: | |||
| 4.0000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.60 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 8.00 (μg/capita/day) | ||
| Structure Class: | III | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 1.00000 | 20.00000 | |
| beverages(nonalcoholic): | 1.30000 | 2.00000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | 8.00000 | |
| fruit ices: | - | 8.00000 | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | 1.00000 | 20.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | - | - | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Flavouring Group Evaluation 33 (FGE.33)[1] - Six Tetrahydrofuran Derivatives from Chemical Groups 13, 14, 16 and 26 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
| Flavouring Group Evaluation 75 (FGE.75)[1] - Consideration of tetrahydrofuran derivatives and a furanone derivative evaluated by JECFA (63rd meeting) structurally related to tetrahydrofuran derivatives evaluated by EFSA in FGE.33 (2008) View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 75, Revision 1 (FGE.75Rev1): Consideration of tetrahydrofuran derivatives evaluated by JECFA (63rd meeting) structurally related to tetrahydrofuran derivatives evaluated by EFSA in FGE.33 (2008) View page or View pdf |
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):637-64-9 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :12506 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| oxolan-2-ylmethyl acetate |
| Chemidplus:0000637649 |
| oxolan-2-ylmethyl acetate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 637-64-9 |
| Pubchem (cid): | 12506 |
| Pubchem (sid): | 134978523 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | HMDB31176 |
| FooDB: | FDB003195 |
| Export Tariff Code: | 2933.19.4300 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
| bread | |
| strawberry | |
| tequila |
| 2- | acetoxymethyl oxolane |
| 2-( | acetoxymethyl) tetrahydrofuran |
| 2-( | acetoxymethyl)oxolane |
| acetoxymethyl)tetrahydrofuran | |
| 2-( | acetoxymethyl)tetrahydrofuran |
| 2- | furanmethanol, tetrahydro-, acetate |
| furfuryl alcohol, tetrahydro-, acetate | |
| oxolan-2-ylmethyl acetate | |
| tetrahydro furfuryl acetate | |
| tetrahydro-2-furan methanol acetate | |
| tetrahydro-2-furanmethanol acetate | |
| tetrahydro-2-furanylmethyl acetate | |
| tetrahydro-2-furyl methyl acetate | |
| tetrahydro-2-furylmethyl acetate | |
| tetrahydrofuran-2-ylmethyl acetate | |
| tetrahydrofurfuryl acetate natural | |
| tetrahydrofurfurylacetate |
| None found yet. Try the PubMed Search. |
