| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 56038-13-2 |
| ECHA EC Number: | 259-952-2 |
| FDA UNII: | 96K6UQ3ZD4 |
| Category: | sweeteners, flavor enhancers |
| IUPAC Name: | sucralose |
| InChI : | InChI=1/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1 |
| Std.InChI: | InChI=1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1 |
| InChIKey : | BAQAVOSOZGMPRM-QBMZZYIRBF |
| Std.InChIKey: | BAQAVOSOZGMPRM-QBMZZYIRSA-N |
| SMILES : | C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CCl)O)O)CCl)O)O)Cl)O |
| MDL: | MFCD03648615 |
| Molar Refractivity : | 80.75 ± 0.4 cm3 (est) |
| Parachor : | 694.4 ± 6.0 cm3 (est) |
| Index of Refraction : | 1.604 ± 0.03 (est) |
| Surface Tension : | 76.5 ± 5.0 dyne/cm (est) |
| Density : | 1.69 ± 0.1 g/cm3 (est) |
| Polarizability : | 32.01 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Additive: | Sucralose |
| GSFA Codex: | Sucralose (Trichlorogalactosucrose) (955) |
| DG SANTE Food Additives: | sucralose |
| FDA Mainterm (SATF): | 56038-13-2 ; SUCRALOSE |
| FDA Regulation: | |
| FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Subpart I--Multipurpose Additives Sec. 172.831 Sucralose. | |
| Appearance: | white crystalline powder (est) |
| Assay: | 98.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 130.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 669.43 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 678.00 °F. TCC ( 358.70 °C. ) (est) |
| logP (o/w): | 0.229 (est) |
| Soluble in: | |
| water, 2.275e+004 mg/L @ 25 °C (est) | |
| alcohol | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | skin conditioning |
| Allan Chemical |
| Sucralose |
| Anhui Haibei |
| Sucralose |
| Atlantic Chemicals |
| Sucralose |
| BOC Sciences |
| For experimental / research use only. |
| Sucralose >98% Odor: characteristic Use: Sucralose is an artificial and noncaloric sweetener, not broken down by the body. |
| Carbosynth |
| For experimental / research use only. |
| Sucralose |
| ECSA Chemicals |
| SUCRALOSE 100 MESH |
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| ECSA Chemicals |
| SUCRALOSE |
| Flavorchem |
| Sucralose |
| Foodchem International |
| Compound Sweetener |
| Foodchem International |
| Sucralose |
| Glentham Life Sciences |
| Sucralose, USP grade |
| Glentham Life Sciences |
| Sucralose |
| Graham Chemical |
| Sucralose |
| Jiangyin Healthway |
| Sucralose |
| New functional food ingredients |
| Kraft Chemical |
| Sucralose |
| OQEMA |
| Sucralose |
| Prinova |
| Sucralose FCC |
| Qingdao Dacon Trading |
| Sucralose |
| Sigma-Aldrich |
| For experimental / research use only. |
| Sucralose analytical standard |
| Sinofi Food Ingredients |
| Sucralose Flavor: characteristic Sugar Substitutes, Chewing Gum, Dairy Products, Confections, Baking Food, Yogurt, Desserts, Alcoholic Beverages, Beverage Powder, Instant Coffee, Chai Tea, Gelatins, Puddings, Ice Cream, Cosmetics, Feed, Pharmaceutical. |
| SRS Aromatics |
| SUCRALOSE (FG) |
| Tate & Lyle |
| SPLENDA® Sucralose |
| Tianjin Talent Chemical |
| Sucralose |
| United International |
| TGS Sucralose |
| Viachem |
| Sucralose – Powder and Liquid Flavor: sweet Sucralose, C12H19Cl3O8, is a zero-calorie high-intensity, non-nutritive sweetener. Sucralose is approximately 600 times as sweet as sucrose (table sugar), twice as sweet as saccharin, and 3.3 times as sweet as aspartame. It is stable under heat and over a broad range of pH conditions. Therefore, it can be used in baking or in products that require a longer shelf life. The commercial success of sucralose-based products stems from its favorable comparison to other low-calorie sweeteners in terms of taste, stability, and safety. Sucralose is typically added to foods in very small quantities. It can be found in more than 4,500 food and beverage products and is used because it is a no-calorie sweetener, does not promote dental cavities, and is safe for consumption by diabetics. Sucralose is used as a replacement for, or in combination with, other artificial or natural sweeteners such as aspartame, acesulfame potassium (Ace-K) or high-fructose corn syrup. Sucralose is used in products such as candy, breakfast bars and soft drinks. It is also used in canned fruits wherein water and sucralose take the place of much higher calorie corn syrup based additives. |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| unreported-mouse LD50 > 16000 mg/kg Trends in Biochemical Sciences. Vol. 3, Pg. 61, 1978. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| sweeteners, flavor enhancers | |||
| Recommendation for sucralose usage levels up to: | |||
| not for fragrance use. | |||
| European Food Safety Authority (EFSA) reference(s): |
| Safety of the proposed extension of use of sucralose (E 955) in foods for special medical purposes in young children View page or View pdf |
| Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute View page or View pdf |
| Outcome of the public consultation on a draft protocol for assessing exposure to sweeteners as part of their safety assessment under the food additives re-evaluation programme View page or View pdf |
| EPI System: View |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :71485 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol |
| Chemidplus:0056038132 |
| (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 56038-13-2 |
| Pubchem (cid): | 71485 |
| Pubchem (sid): | 135029485 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C12285 |
| HMDB (The Human Metabolome Database): | HMDB31554 |
| FooDB: | FDB008166 |
| FDA Listing of Food Additive Status: | View |
| ChemSpider: | View |
| Wikipedia: | View |
| EFSA Update of results on the monitoring of furan levels in food: | Read Report |
| EFSA Previous report: Results on the monitoring of furan levels in food: | Read Report |
| EFSA Report of the CONTAM Panel on provisional findings on furan in food: | Read Report |
| Formulations/Preparations: aqueous solutions | |
| None Found |
| not found in nature |
| (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis( | chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol |
| 1,6- | dichlor-1,6-dideoxy-β-D-fructofuranosyl-4-chlor-4-deoxy-a-D-galactopyranoside |
| 1,6- | dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-a-D-galactose |
| 1,6- | dichloro-1,6-dideoxy-b-D-fructofuranosyl-4-chloro-4-deoxy-a-D-galacotopyranoside |
| 1,6- | dichloro-1,6-dideoxy-b-D-fructofuranosyl-4-chloro-4-deoxy-a-D-galactopyranoside |
| a-D- | galactopyranoside, 1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy- |
| splenda | |
| 4,1',6'- | trichloro-4,1',6'-trideoxy-galacto-sucrose |
| trichlorogalactosucrose | |
| 1',4,6'- | trichlorogalactosucrose |
| trichlorosucrose |
