| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 56-81-5 |
| ECHA EC Number: | 200-289-5 |
| FDA UNII: | PDC6A3C0OX |
| CoE Number: | 11894 |
| Category: | solvents/deluents for cosmetic, flavor and/or fragrance agents |
| IUPAC Name: | glycerine |
| InChI : | InChI=1/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2 |
| Std.InChI: | InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2 |
| InChIKey : | PEDCQBHIVMGVHV-UHFFFAOYAF |
| Std.InChIKey: | PEDCQBHIVMGVHV-UHFFFAOYSA-N |
| SMILES : | C(C(CO)O)O |
| MDL: | MFCD00004722 |
| Molar Refractivity : | 20.51 ± 0.3 cm3 (est) |
| Parachor : | 199.0 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.489 ± 0.02 (est) |
| Surface Tension : | 61.9 ± 3.0 dyne/cm (est) |
| Density : | 1.297 ± 0.06 g/cm3 (est) |
| Polarizability : | 8.13 ± 0.5 10-24cm3 (est) |
| Appearance: | colorless clear oily liquid (est) |
| Assay: | 95.00 to 100.00 |
| Food Chemicals Codex Listed: | Yes |
| Specific Gravity: | 1.25700 to 1.27000 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 10.459 to 10.568 |
| Refractive Index: | 1.46700 to 1.48100 @ 20.00 °C. |
| Melting Point: | 17.00 to 20.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 181.00 to 182.00 °C. @ 20.00 mm Hg |
| Boiling Point: | 290.00 to 291.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.000168 mmHg @ 25.00 °C. |
| Vapor Density: | 3.1 ( Air = 1 ) |
| Flash Point: | 320.00 °F. TCC ( 160.00 °C. ) |
| logP (o/w): | -1.850 (est) |
| Shelf Life: | 24.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: | |
| alcohol | |
| water, 1e+006 mg/L @ 25 °C (est) | |
| water, 1.00E+06 mg/L @ 25 °C (exp) | |
| Insoluble in: | |
| paraffin oil | |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
| R 36 - Irritating to eyes. S 02 - Keep out of the reach of children. S 25 - Avoid contact with eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/39 - Wear suitable clothing and eye/face protection. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 12600 mg/kg BEHAVIORAL: GENERAL ANESTHETICLIVER: OTHER CHANGESBEHAVIORAL: MUSCLE WEAKNESS Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945. intravenous-rat LD50 5566 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976. intraperitoneal-rat LD50 4420 mg/kg CARDIAC: OTHER CHANGESBEHAVIORAL: TOXIC PSYCHOSISKIDNEY, URETER, AND BLADDER: OTHER CHANGES Research Communications in Chemical Pathology and Pharmacology. Vol. 56, Pg. 125, 1987. oral-rabbit LD50 27000 mg/kg Delaware State Medical Journal. Vol. 31, Pg. 276, 1959. intravenous-rabbit LD50 53000 mg/kg Drugs in Japan Vol. 6, Pg. 215, 1982. oral-mouse LD50 4090 mg/kg Farmatsevtichnii Zhurnal Vol. (6), Pg. 56, 1977. intravenous-mouse LD50 4250 mg/kg Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 583, 1950. intraperitoneal-mouse LD50 8700 mg/kg BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1579, 1978. oral-guinea pig LD50 7750 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941. oral-human LDLo 1428 mg/kg BEHAVIORAL: HEADACHEGASTROINTESTINAL: NAUSEA OR VOMITING "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 288, 1969. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 > 10000 mg/kg BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 9-4/1970 subcutaneous-rat LD50 100 mg/kg Drugs in Japan Vol. 6, Pg. 215, 1982. subcutaneous-mouse LD50 91 mg/kg Drugs in Japan Vol. 6, Pg. 215, 1982. | |
| Inhalation Toxicity: | |
| inhalation-rat LC50 > 570 mg/m3/1H BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 9-4/1970 | |
| Category: | |||
| solvents/deluents for cosmetic, flavor and/or fragrance agents | |||
| Recommendation for glycerine usage levels up to: | |||
| not for fragrance use. | |||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 3. Update in publication number(s): 29 | |||
| Click here to view publication 3 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 18.00000 | 1300.00000 | |
| beverages(nonalcoholic): | 0.70000 | 570.00000 | |
| beverages(alcoholic): | 20000.00000 | 20000.00000 | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | 17.00000 | 6000.00000 | |
| condiments / relishes: | - | - | |
| confectionery froastings: | 70.00000 | 23000.00000 | |
| egg products: | - | - | |
| fats / oils: | 0.20000 | 0.20000 | |
| fish products: | - | - | |
| frozen dairy: | 0.30000 | 500.00000 | |
| fruit ices: | - | - | |
| gelatins / puddings: | 26.00000 | 360.00000 | |
| granulated sugar: | - | - | |
| gravies: | 0.20000 | 0.20000 | |
| hard candy: | 22.00000 | 980.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | 42.00000 | 54.00000 | |
| meat products: | 1.00000 | 40.00000 | |
| milk products: | 84.00000 | 84.00000 | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | 0.02000 | 0.07000 | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | 40000.00000 | 40000.00000 | |
| snack foods: | 22.00000 | 24.00000 | |
| soft candy: | 2.00000 | 4.00000 | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | 74.00000 | 74.00000 | |
| European Food Safety Authority (EFSA) reference(s): |
| Re-evaluation of glycerol (E 422) as a food additive View page or View pdf |
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| NIOSH International Chemical Safety Cards:search |
| NIOSH Pocket Guide:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA Substance Registry Services (TSCA):56-81-5 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :753 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| propane-1,2,3-triol |
| Chemidplus:0000056815 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:56-81-5 |
| propane-1,2,3-triol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 56-81-5 |
| Pubchem (cid): | 753 |
| Pubchem (sid): | 134972920 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00116 |
| HMDB (The Human Metabolome Database): | HMDB00131 |
| FooDB: | FDB000756 |
| YMDB (Yeast Metabolome Database): | YMDB00283 |
| Export Tariff Code: | 2905.45.0000 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| None Found |
| denaturants | |
| humectants | |
| solvents |
| bulbold | |
| cristal | |
| glyceol | |
| glycerin | |
| glycerin organic | |
| glycerine 99.5 USP | |
| glycerine 99.7 USP | |
| glycerine FCC | |
| glycerine natural USP/EP/BP/JP grade | |
| glycerine regular grade | |
| glycerine U.S.P. | |
| glycerine, natural | |
| glycerol | |
| 3H- | glycerol |
| glycyl alcohol | |
| mackstat H 66 | |
| pricerine 9091 | |
| propan-1,2,3-triol | |
| 1,2,3- | propane triol |
| propane-1,2,3-triol | |
| 1,2,3- | propanetriol |
| trihydroxypropane | |
| 1,2,3- | trihydroxypropane |
| tryhydroxypropane | |
| zilgel Oil | |
| zilgel SM | |
| zilgel VV |
