| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 56-40-6 |
| ECHA EC Number: | 200-272-2 |
| FDA UNII: | TE7660XO1C |
| CoE Number: | 11771 |
| Category: | special dietary and nutritional additives, acidity regulators |
| IUPAC Name: | glycine |
| InChI : | InChI=1/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5) |
| Std.InChI: | InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5) |
| InChIKey : | DHMQDGOQFOQNFH-UHFFFAOYAW |
| Std.InChIKey: | DHMQDGOQFOQNFH-UHFFFAOYSA-N |
| SMILES : | C(C(=O)O)N |
| MDL: | MFCD00008131 |
| Molar Refractivity : | 16.41 ± 0.3 cm3 (est) |
| Parachor : | 162.5 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.460 ± 0.02 (est) |
| Surface Tension : | 54.4 ± 3.0 dyne/cm (est) |
| Density : | 1.254 ± 0.06 g/cm3 (est) |
| Polarizability : | 6.50 ± 0.5 10-24cm3 (est) |
| Appearance: | white crystalline powder (est) |
| Assay: | 99.00 to 100.00 |
| Food Chemicals Codex Listed: | Yes |
| Melting Point: | 240.00 to 245.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 240.94 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.012000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 211.00 °F. TCC ( 99.50 °C. ) (est) |
| logP (o/w): | -0.928 (est) |
| Soluble in: | |
| water, 6.256e+005 mg/L @ 25 °C (est) | |
| water, 2.49E+05 mg/L @ 25 °C (exp) | |
| Insoluble in: | |
| alcohol | |
| ether | |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| None - None found. | |
| S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 7930 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. intravenous-rat LD50 2600 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. oral-mouse LD50 4920 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. intravenous-mouse LD50 2370 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. intraperitoneal-mouse LD50 4450 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. intravenous-cat LDLo 3000 mg/kg BEHAVIORAL: MUSCLE WEAKNESSBEHAVIORAL: FOOD INTAKE (ANIMAL)BEHAVIORAL: ATAXIA Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 306, 1942. | |
| Dermal Toxicity: | |
| subcutaneous-rat LD50 5200 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. subcutaneous-mouse LD50 5060 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 5, Pg. 1502, 1977. | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| special dietary and nutritional additives, acidity regulators | |||
| Recommendation for glycine usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 135.00 (μg/capita/day) | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 5. Update in publication number(s): 15, 27 | |||
| Click here to view publication 5 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 50.00000 | 150.00000 | |
| beverages(nonalcoholic): | 250.00000 | 1000.00000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | 150.00000 | 3000.00000 | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | 150.00000 | 4000.00000 | |
| hard candy: | 25.00000 | 150.00000 | |
| imitation dairy: | 50.00000 | 150.00000 | |
| instant coffee / tea: | 150.00000 | 150.00000 | |
| jams / jellies: | 50.00000 | 150.00000 | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | 25.00000 | 150.00000 | |
| soups: | 150.00000 | 6000.00000 | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
| Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
| Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008) View page or View pdf |
| Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1] View page or View pdf |
| Scientific Opinion on the safety and efficacy of the use of amino acids (chemical group 34) when used as flavourings for all animal species View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list View page or View pdf |
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA Substance Registry Services (TSCA):56-40-6 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :750 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| 2-aminoacetic acid |
| Chemidplus:0000056406 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:MB7600000 for cas# 56-40-6 |
| 2-aminoacetic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 56-40-6 |
| Pubchem (cid): | 750 |
| Pubchem (sid): | 134972608 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00037 |
| HMDB (The Human Metabolome Database): | HMDB00123 |
| FooDB: | FDB000484 |
| YMDB (Yeast Metabolome Database): | YMDB00016 |
| Export Tariff Code: | 2922.40 |
| FDA Listing of Food Additive Status: | View |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: •usepaopp pesticide code 103401; trade names: topsin; cercobin; cleary's 3336. former trade names•aminoacetic acid nf soln, sterile, 1.1%; 1 l, 2 l, 4 l, & 20 l bottles.•irrigation usp: 1.5%1500, 2000 & 3000 ml, 15% (concentrate)1000 ml.•grades: technical; nf; fcc. | |
| None Found |
| antistatic agents | |
| buffering agents | |
| hair conditioning | |
| skin conditioning |
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| lettuce leaf |
| acetic acid, amino- | |
| acide aminoacetique | |
| aciport | |
| amino-acetic acid | |
| amino-aceticacid | |
| aminoacetic acid | |
| 2- | aminoacetic acid |
| aminoazijnzuur | |
| aminoessigsaeure | |
| aminoethanoic acid | |
| amitone | |
| corilin | |
| glicoamin | |
| glycine USP | |
| glycoamin | |
| glycocoll | |
| glycolixir | |
| glykokoll | |
| glyzin | |
| gyn-hydralin | |
| hgly | |
| leimzucker | |
| padil |
