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laevo-carnitine tartrate

masking agents
2D:
3D:
CAS Number: 36687-82-8
FDA UNII: 4D8F2Q45LQ
Category: masking agents
IUPAC Name: laevo-carnitine tartrate
InChI : InChI=1/C11H19NO8/c1-12(2,3)5-6(4-7(13)14)20-11(19)9(16)8(15)10(17)18/h6,8-9,15-16H,4-5H2,1-3H3,(H-,13,14,17,18)
Std.InChI: InChI=1S/C11H19NO8/c1-12(2,3)5-6(4-7(13)14)20-11(19)9(16)8(15)10(17)18/h6,8-9,15-16H,4-5H2,1-3H3,(H-,13,14,17,18)
InChIKey : JHQQFDNWUBVPIM-UHFFFAOYAD
Std.InChIKey: JHQQFDNWUBVPIM-UHFFFAOYSA-N
SMILES : C[N+](C)(C)CC(CC(=O)[O-])OC(=O)C(C(C(=O)O)O)O
MDL: MFCD04974128

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FDA/DG SANTE Petitions, Reviews, Notices:
GRN 935 L-carnitine-L-tartrate View - notice PDF
FEMA Number:4906 L-carnitine tartrate
FDA:No longer provide for the use of these seven synthetic flavoring substances

Physical Properties:

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
water, 1e+006 mg/L @ 25 °C (est)

Cosmetic Information:

CosIng:cosmetic data
Cosmetic Uses: fragrance

Suppliers:

Atlantic Chemicals
L-Carnitine Tartrate
BOC Sciences
For experimental / research use only.
L-Carnitine-L-Tartrate > 95%
ECSA Chemicals
L-CARNITINE TARTRATE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Foodchem International
L-Carnitine L-Tartrate
Glentham Life Sciences
L-Carnitine tartrate
Indis NV
For experimental / research use only.
L-Carnitine Tartrate
Penta International
L-CARNITINE TARTRATE
Qingdao Dacon Trading
L-Carnitine Tartrate
Santa Cruz Biotechnology
For experimental / research use only.
L-Carnitine Tartrate ≥98%
TCI AMERICA
For experimental / research use only.
L-Carnitine L-Tartrate >98.0%(T)
United International
L-Carnitine Tartrate

Safety Information:

Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
masking agents
Recommendation for laevo-carnitine tartrate usage levels up to:
not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 29
Click here to view publication 29
average usual ppmaverage maximum ppm
baked goods: 750.000001250.00000
beverages(nonalcoholic): 750.000001250.00000
beverages(alcoholic): 750.000001250.00000
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: 750.000001250.00000
confectionery froastings: --
egg products: --
fats / oils: 750.000001250.00000
fish products: 750.000001250.00000
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 750.000001250.00000
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 750.000001250.00000
milk products: --
nut products: --
other grains: 750.000001250.00000
poultry: 750.000001250.00000
processed fruits: --
processed vegetables: 750.000001250.00000
reconstituted vegetables: --
seasonings / flavors: --
snack foods: 750.000001250.00000
soft candy: --
soups: 750.000001250.00000
sugar substitutes: --
sweet sauces: --

Safety References:

European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety and efficacy of L-carnitine and L-carnitine L-tartrate as feed additives for all animal species based on a dossier submitted by Lonza Benelux BV
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24720998
National Institute of Allergy and Infectious Diseases:Data
(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate;2,3,4,4-tetrahydroxybutanoic acid
Chemidplus:0036687828

References:

(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate;2,3,4,4-tetrahydroxybutanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):24720998
Pubchem (sid):152164538

Other Information:

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:3302.90.0010
FDA Listing of Food Additive Status:View
ChemSpider:View

Potential Blenders and core components :

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):

not found in nature

Synonyms:

3-[(3-carboxy-2,3-dihydroxypropanoyl)oxy]-4-(trimethylammonio)butanoate
L-carnitine L-tartrate
L-carnitine tartrate
(3R)-3-hydroxy-4-(trimethylazaniumyl)butanoate;2,3,4,4-tetrahydroxybutanoic acid
1-propanaminium, 3-carboxy-2-(3-carboxy-2,3-dihydroxy-1-oxopropoxy)-N,N,N-trimethyl-, inner salt

Articles:

PubMed:Effect of a carbohydrate-protein multi-ingredient supplement on intermittent sprint performance and muscle damage in recreational athletes.
PubMed:Effects of ingestion of a commercially available thermogenic dietary supplement on resting energy expenditure, mood state and cardiovascular measures.
PubMed:Topical and transdermal delivery of L-carnitine.
PubMed:Effects of exercise intensity and altered substrate availability on cardiovascular and metabolic responses to exercise after oral carnitine supplementation in athletes.
PubMed:Chronic oral ingestion of L-carnitine and carbohydrate increases muscle carnitine content and alters muscle fuel metabolism during exercise in humans.
PubMed:Effects of oral L-carnitine supplementation on insulin sensitivity indices in response to glucose feeding in lean and overweight/obese males.
PubMed:l-Carnitine l-tartrate supplementation favorably affects biochemical markers of recovery from physical exertion in middle-aged men and women.
PubMed:Carnitine status of pregnant women: effect of carnitine supplementation and correlation between iron status and plasma carnitine concentration.
PubMed:Carbohydrate, protein, and fat metabolism during exercise after oral carnitine supplementation in humans.
PubMed:Effects of carnitine supplementation on flow-mediated dilation and vascular inflammatory responses to a high-fat meal in healthy young adults.
PubMed:Effects of L-carnitine L-tartrate supplementation on muscle oxygenation responses to resistance exercise.
PubMed:Dietary l-carnitine supplementation improves bone mineral density by suppressing bone turnover in aged ovariectomized rats.
PubMed:L-carnitine-L-tartrate promotes human hair growth in vitro.
PubMed:Indications that topical L-carnitin-L-tartrate promotes human hair growth in vivo.
PubMed:Mechanistic analysis for drug permeation through intestinal membrane.
PubMed:Responses of criterion variables to different supplemental doses of L-carnitine L-tartrate.
PubMed:L-Carnitine L-tartrate (LCLT) and dehydroepiandrosterone sulfate (DHEAS) affect red and white blood cells in aged Sprague-Dawley rats.
PubMed:Androgenic responses to resistance exercise: effects of feeding and L-carnitine.
PubMed:Effects of four weeks L-carnitine L-tartrate ingestion on substrate utilization during prolonged exercise.
PubMed:Effects of acute versus chronic L-carnitine L-tartrate supplementation on metabolic responses to steady state exercise in males and females.
PubMed:Free and total carnitine concentrations in pig plasma after oral ingestion of various L-carnitine compounds.
PubMed:The effects of L-carnitine L-tartrate supplementation on hormonal responses to resistance exercise and recovery.
PubMed:L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress.
PubMed:Safety measures of L-carnitine L-tartrate supplementation in healthy men.
PubMed:Epididymal markers in rats exposed to the xenoestrogen p-nonylphenol: no biochemical effects at low dosages.
PubMed:Physiological mechanism for enhancement of paracellular drug transport.
PubMed:Modulation of neutrophil superoxide generation by inhibitors of protein kinase C, calmodulin, diacylglycerol and myosin light chain kinases, and peptidyl prolyl cis-trans isomerase.
PubMed:[Resolution of the racemates of DL-carnitine].
PubMed:The resolution of (plus or minus)-carnitine and the synthesis of acylcarnitines.
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