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peg-90

humectants, solvents
2D:
3D:
CAS Number: 25322-68-3
ECHA EC Number: 500-038-2
FDA UNII: Search
Category: humectants, solvents
IUPAC Name: peg-90

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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Physical Properties:

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No

Cosmetic Information:

Suppliers:

None found

Safety Information:

Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-dog LDLo 3000 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.

oral-guinea pig LD50 15700 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-guinea pig LD50 17000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-guinea pig LD50 19600 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-guinea pig LD50 22500 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950.

oral-guinea pig LD50 28000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-guinea pig LD50 28900 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-guinea pig LD50 50000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-guinea pig LD50 50900 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-mouse LD50 473 mg/kg
Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 21, Pg. 387, 1986.

intraperitoneal-mouse LD50 2000 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.

intraperitoneal-mouse LD50 7500 mg/kg
National Technical Information Service. Vol. AD628-313

intraperitoneal-mouse LD50 8000 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 103, Pg. 293, 1951.

intravenous-mouse LD50 7900 ug/kg
Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 316, 1970.

intravenous-mouse LD50 8550 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

intravenous-mouse LD50 16000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-mouse LD50 28915 mg/kg
Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.

oral-mouse LD50 31000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-mouse LD50 34000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-mouse LD50 36000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

intravenous-rabbit LD50 8000 mg/kg
BLOOD: CHANGE IN CLOTTING FACTORS
Kriobiologiya i Kriomeditsina. Cryobiology and Cryomedicine. Vol. 4, Pg. 71, 1978.

oral-rabbit LD50 14000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-rabbit LD50 17300 mg/kg
International Journal of Toxicology. Vol. 18(Suppl

oral-rabbit LD50 17300 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rabbit LD50 19000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-rabbit LD50 26800 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rabbit LD50 28900 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rabbit LD50 76000 mg/kg
International Journal of Toxicology. Vol. 18(Suppl

oral-rabbit LD50 76000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD > 4000 mg/kg
Union Carbide Data Sheet. Vol. 9/25/1969

intraperitoneal-rat LD50 6790 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-rat LD50 9000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-rat LD50 9700 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982.

intraperitoneal-rat LD50 9708 mg/kg
Proceedings of the European Society of Toxicology. Vol. 17, Pg. 351, 1976.

intraperitoneal-rat LD50 12600 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-rat LD50 14100 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982.

intraperitoneal-rat LD50 15390 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-rat LD50 15570 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-rat LD50 16000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intraperitoneal-rat LD50 17000 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950.

intraperitoneal-rat LD50 17700 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

intravenous-rat LD50 7130 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982.

intravenous-rat LD50 7312 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

intravenous-rat LD50 7500 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3849, 1982.

intravenous-rat LD50 13000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD50 600 mg/kg
Dow Chemical Company Reports. Vol. MSD-94

oral-rat LD50 1054 mg/kg
Dow Chemical Company Reports. Vol. MSD-95

oral-rat LD50 > 4000 mg/kg
Dow Chemical Company Reports. Vol. MSD-938

oral-rat LD50 22000 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969.

oral-rat LD50 27500 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD50 28000 mg/kg
Dow Chemical Company Reports. Vol. MSD-1112

oral-rat LD50 30000 mg/kg
Dow Chemical Company Reports. Vol. MSD-2203

oral-rat LD50 30200 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 39, Pg. 349, 1950.

oral-rat LD50 31600 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969.

oral-rat LD50 31640 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD50 32000 mg/kg
Dow Chemical Company Reports. Vol. MSD-937

oral-rat LD50 44200 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD50 45000 mg/kg
"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3847, 1982.

oral-rat LD50 50000 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 747, 1969.

oral-rat LD50 > 50000 mg/kg
Dow Chemical Company Reports. Vol. MSD-935

oral-rat LD50 > 50000 mg/kg
Dow Chemical Company Reports. Vol. MSD-940

oral-rat LD50 50000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD50 51200 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

oral-rat LD50 51310 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

unreported-rat LD50 7800 mg/kg
United States Patent Document. Vol. #4767763

intravenous-rat LDLo 3 mg/kg
Toxicology and Applied Pharmacology. Vol. 16, Pg. 442, 1970.

intravenous-rat LDLo 22000 mg/kg
KIDNEY, URETER, AND BLADDER: HEMATURIAVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTIONCARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)
Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 1087, 1973.

Dermal Toxicity:
subcutaneous-mouse LD50 18000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

skin-rabbit LD > 1000 mg/kg
Union Carbide Data Sheet. Vol. 9/25/1969

skin-rabbit LD50 > 20 mL/kg
International Journal of Toxicology. Vol. 18(Suppl

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-1112

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-2202

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-96

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-2203

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-937

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-939

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-935

skin-rabbit LD50 > 20000 mg/kg
Dow Chemical Company Reports. Vol. MSD-940

subcutaneous-rat LD50 16000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Arzneimittel-Forschung. Drug Research. Vol. 3, Pg. 451, 1953.

Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
humectants, solvents
Recommendation for peg-90 usage levels up to:
not for fragrance use.
Recommendation for peg-90 flavor usage levels up to:
not for flavor use.

Safety References:

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):25322-68-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
Chemidplus:0025322683
EPA/NOAA CAMEO:hazardous materials

References:

Canada Domestic Sub. List:25322-68-3
Pubchem (sid):134996364

Other Information:

Potential Blenders and core components :

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):

not found in nature

Synonyms:

poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (90 mol EO average molar ratio)
polyethylene glycol (90)
polyoxyethylene (90)

Articles:

None found yet. Try the PubMed Search.
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