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sodium lauryl sulfate

emulsifiers, surfactants
2D:
3D:
CAS Number: 151-21-3
ECHA EC Number: 205-788-1
FDA UNII: 368GB5141J
Category: emulsifiers, surfactants
IUPAC Name: sodium lauryl sulfate
InChI : InChI=1/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
Std.InChI: InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
InChIKey : DBMJMQXJHONAFJ-REWHXWOFAO
Std.InChIKey: DBMJMQXJHONAFJ-UHFFFAOYSA-M
SMILES : CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]
MDL: MFCD00036175

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:Search
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FEMA Number:4437 sodium lauryl sulfate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):151-21-3 ; SODIUM LAURYL SULFATE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart C--Coatings, Films and Related Substances
Sec. 172.210 Coatings on fresh citrus fruit.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart I--Multipurpose Additives
Sec. 172.822 Sodium lauryl sulfate.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.320 Resinous and polymeric coatings for polyolefin films.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.180 Components of paper and paperboard in contact with dry food.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.210 Defoaming agents used in the manufacture of paper and paperboard.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1200 Cellophane.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1210 Closures with sealing gaskets for food containers.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1630 Polyethylene phthalate polymers.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2600 Rubber articles intended for repeated use.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2800 Textiles and textile fibers.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3400 Emulsifiers and/or surface-active agents.


FDA PART 179 -- IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF FOOD
Subpart C--Packaging Materials for Irradiated Foods
Sec. 179.45 Packaging materials for use during the irradiation of prepackaged foods.

Physical Properties:

Appearance:white crystalline powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 205.50 °C. @ 760.00 mm Hg
Boiling Point: 204.00 to 207.00 °C. @ 760.00 mm Hg
Flash Point:> 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 1.600
Soluble in:
alcohol
water, 1.00E+05 mg/L @ 25 °C (exp)

Suppliers:

Achiewell
For experimental / research use only.
Sodium Lauryl Sulfate (SLS)
Acme-Hardesty
Sodium Lauryl Sulfate Powder
Odor: characteristic
Use: Detergent, toothpaste, wetting agent and more.
Acme-Hardesty
Sodium Lauryl Sulfate
Odor: characteristic
Use: Flow Agent, Internal Lubricant, Excipient and more.
Allan Chemical
Sodium Lauryl Sulfate
BOC Sciences
For experimental / research use only.
SLES
Charkit Chemical
SODIUM LAURYL SULFATE
Chemical-navi - Nikkol
NIKKOL SLS-JP
Odor: characteristic
Use: Used as a foaming Agent or detergent for tough oil-based stains.
Chemical-navi - Nikkol
NIKKOL SLS
Odor: characteristic
Use: Foaming and cleansing agent; suitable especially for products needing degreasing power.
ECSA Chemicals
SODIUM LAURYL SULFATE 30%
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
SODIUM LAURYL SULFATE 30%
ECSA Chemicals
SODIUMLAURYLSULFATE
ECSA Chemicals
SODIUMLAURYLSULFATE
Glentham Life Sciences
Sodium dodecyl sulfate, 10% solution in water
Glentham Life Sciences
Sodium dodecyl sulfate, 20% solution in water
Glentham Life Sciences
Sodium dodecyl sulfate, 99%
Glentham Life Sciences
Sodium dodecyl sulfate, Ph. Eur., USP grade
Graham Chemical
Sodium Lauryl Sulfate (Performer Alkyl Ether Sulfate G503)
Hebei Daou Technology
Sodium Lauryl Sulfate
Indis NV
For experimental / research use only.
Sodium Lauryl Sulfate
Kao Corporation
EMAL 0
Odor: characteristic
Use: Foaming agent and booster of tooth pastes and shampoos.
Kao Corporation
EMAL 0S
Odor: characteristic
Use: Foaming agent and booster of tooth pastes and shampoos.
Kao Corporation
EMAL 10G
Odor: characteristic
Use: Foaming agent and detergent for cosmetics and pharmaceuticals
Kao Corporation
EMAL 10N
Odor: characteristic
Use: Toothpastes
Kao Corporation
EMAL 10P-HD
Odor: characteristic
Use: Toothpastes
Kao Corporation
EMAL 10PT
Odor: characteristic
Use: Foaming agent and detergent for cosmetics and pharmaceuticals, Wetting agent for wettable powders
Kao Corporation
EMAL 2F PASTE
Odor: characteristic
Use: Foaming agent and booster of tooth pastes and shampoos.
Kao Corporation
EMAL 2F-30
Odor: characteristic
Use: Emulsifier for polymerization process of synthetic rubber and synthetic resin
Kao Corporation
EMAL 30E
Odor: characteristic
Use: Shampoos and body shampoos, hard surface liquid detergents and laundry products
Kraft Chemical
Sodium Lauryl Sulfate
Penta International
SODIUM LAURYL SULFATE FCC
Penta International
SODIUM LAURYL SULFATE NF
Penta International
SODIUM LAURYL SULFATE NF/EP/JP
Sarchem Laboratories
For experimental / research use only.
Sodium Lauryl Sulfate
Sigma-Aldrich
For experimental / research use only.
Sodium dodecyl sulfate BioXtra, ≥99.0% (GC)
Stepan Company
POLYSTEP® B-24
Stepan Company
POLYSTEP® B-3
Stepan Company
STEPANOL® 360
Stepan Company
STEPANOL® DX-AS165 N
Stepan Company
STEPANOL® DX-AS165 P
Stepan Company
STEPANOL® ME-DRY
Stepan Company
STEPANOL® WA-100 NF/USP
Actives, % 97
Stepan Company
STEPANOL® WA-200 Needles
Stepan Company
STEPANOL® WA-EXTRA HP
Stepan Company
STEPANOL® WA-EXTRA K
Stepan Company
STEPANOL® WA-EXTRA PC
Stepan Company
STEPANOL® WA-EXTRA-E
Stepan Company
STEPANOL® WA-EXTRA
Universal Preserv-A-Chem Inc.
SODIUM LAURYL SULFATE
Odor: characteristic
Use: Is a sodium coco-sulfate derived from natural coconut oil. Heat is required to fully dissolve the product. It provides good lather, thickening and conditioning properties. This product is also a replacement for betaines and alkanolamides in personal cleansing products. A unique, naturally derived anionic surfactant for the formulation of -natural type- personal cleansing products that is preservative-free.

Safety Information:

European information :
Most important hazard(s):
Xi - Irritant
R 36/38 - Irritating to skin and eyes.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36 - Wear suitable protective clothing.
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
Acute toxicity, Oral (Category 4), H302; Acute toxicity, Inhalation (Category 4), H332
Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318
Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
Acute aquatic toxicity (Category 2), H401
Chronic aquatic toxicity (Category 3), H412
GHS Label elements, including precautionary statements
Pictogram
Signal word Danger
Hazard statement(s)
H228 - Flammable solid
H302 + H332 - Harmful if swallowed or if inhaled
H315 - Causes skin irritation
H318 - Causes serious eye damage
H335 - May cause respiratory irritation
H401 - Toxic to aquatic life
H412 - Harmful to aquatic life with long lasting effects
Precautionary statement(s)
P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 - Ground/bond container and receiving equipment.
P241 - Use explosion-proof electrical/ventilating/lighting/…/equipment.
P261 - Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 - Wash skin thouroughly after handling.
P270 - Do not eat, drink or smoke when using this product.
P271 - Use only outdoors or in a well-ventilated area.
P273 - Avoid release to the environment.
P280 - Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P312 + P330 - IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell. Rinse mouth.
P302 + P352 - IF ON SKIN: wash with plenty of soap and water.
P304 + P340 + P312 - IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER or doctor/ physician if you feel unwell.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention.
P362 - Take off contaminated clothing and wash before reuse.
P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction.
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed.
P405 - Store locked up.
P501 - Dispose of contents/ container to an approved waste disposal plant.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 250 mg/kg
VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATIONBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 283, 1953.

intravenous-mouse LD50 118 mg/kg
Journal of Pharmaceutical Sciences. Vol. 52, Pg. 803, 1963.

intraperitoneal-rat LD50 210 mg/kg
Proceedings of the Scientific Section of the Toilet Goods Association. Vol. 3, Pg. 1, 1945.

intravenous-rat LD50 118 mg/kg
Journal of Pharmaceutical Sciences. Vol. 52, Pg. 803, 1963.

oral-rat LD50 1288 mg/kg
Food and Cosmetics Toxicology. Vol. 5, Pg. 763, 1967.

Dermal Toxicity:
skin-rabbit LDLo 10000 mg/kg
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"BEHAVIORAL: ATAXIA
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 23-3/1971

Inhalation Toxicity:
inhalation-rat LC50 > 3900 mg/m3/1H
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 23-3/1971

Safety in Use Information:

Category:
emulsifiers, surfactants
Recommendation for sodium lauryl sulfate usage levels up to:
not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
average usual ppmaverage maximum ppm
baked goods: 0.001000.01000
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: 0.001000.01000
cheese: 0.001000.01000
chewing gum: 0.001000.01000
condiments / relishes: 0.001000.01000
confectionery froastings: 0.001000.01000
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: 0.001000.01000
hard candy: --
imitation dairy: 0.001000.01000
instant coffee / tea: 0.001000.01000
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: 0.001000.01000
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 0.001000.10000
snack foods: 0.001000.01000
soft candy: --
soups: 0.001000.01000
sugar substitutes: 0.001000.01000
sweet sauces: 0.001000.01000

Safety References:

European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):151-21-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :3423265
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 2426
WGK Germany:2
sodium dodecyl sulfate
Chemidplus:0000151213
EPA/NOAA CAMEO:hazardous materials
RTECS:151-21-3

References:

sodium dodecyl sulfate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:151-21-3
Pubchem (cid):3423265
Pubchem (sid):134973420

Other Information:

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
UM BBD:Search
KEGG (GenomeNet):C11166
HMDB (The Human Metabolome Database):HMDB05004
FooDB:FDB020359
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
sodium lauryl sulfate usp: solution 20%; solution 20%, with coal tar solution 10%; solution 20%, with resorcinol 10%.sodium monododecyl sulfate...mixt of sodium alkyl sulfates consisting chiefly of sodium lauryl sulfate. combined content of sodium chloride & sodium sulfate is not more than 8%.the article of commerce is a mixture of analogous sodium alkyl sulfates wih sodium lauryl sulfate predominating.grades: usp; technical; fcc.

Potential Blenders and core components :

None Found

Potential Uses:

cleansing agents

Occurrence (nature, food, other):

not found in nature

Synonyms:

adeka hope LS 35
akyposal NLS
alscoap-LN 90P
avirol SL 2010
berol 474
bio-soft SDBS 60
calfoam ES 303
calfoam SLS-30
carsonol SLS
cosmopon 35
N-dodecyl sulfate sodium
dodecyl sulfate sodium salt
eenapol LSS
emal 0
emal 0S
emal 10G
emal 10N
emal 10P-HD
emal 10PT
emal 2F paste
emal 2F-30
emal 2F30
emal 30E
empicol 0303
empicol LX 2
empicol LXSV 938U
emulsogen LS
lauryl sodium sulfate
lauryl sulfate sodium
lauryl sulfate sodium salt
lauryl sulfate, sodium
neopon LS
nikkol SLS
nikkol SLS-JP
nutrapon W
nutrapon WAC
nutrapon WAQ
perlankrol E.S.D. 60
polirol LS
polystep B 5
polystep B-24
polystep B-3
rewopol NLS 28
rhodapon LX 28 HA
rhodapon UB STD
rolpon LS
rosulfan L 1
sandet ONA
sermul EA 150
silipon RN 6031
sinolin 90TK-N
sintrex L 100
sipon LCS 98
sodium dodecyl sulfate
sodium lauryl sulphate
sodium laurylsulphate
sodium N-dodecyl sulfate
sorpol 5029O
stanfax 234
stepanal WAC
stepanol 360
stepanol DX-AS165 N
stepanol DX-AS165 P
stepanol ME-DRY
stepanol WA-100 NF/USP
stepanol WA-200 Needles
stepanol WA-90
stepanol WA-EXTRA
stepanol WA-EXTRA HP
stepanol WA-EXTRA K
stepanol WA-EXTRA PC
stepanol WA-EXTRA-E
sterling waq-cosmetic
sulfate, sodium dodecyl
sulfate, sodium lauryl
sulfochem SLS
sulfopon WA 1
sulfopon WA2
sulfopon WA3
sulfotex WA
sulfuric acid monododecyl ester sodium salt
sulfuric acid, dodecyl ester, sodium salt
sulfuric acid, monododecyl ester, sodium salt
sunnol LM 1130
supralate C
surfapon L-96
surfapon LCP
surfax 100
surfax 220
swascol 3L
swascol 4L
syntapon L
tarapon K 12
tensopol A 79
texapon K 12
texapon K12
texapon L 100
texapon V HC
trepenol WA
ufarol AM 30
ufarol NA-30
ufarol TCL 92
ultra sulfate SL-1
WAQE
witcolate A
zorapol LS-30

Articles:

Info:Sodium Lauryl Sulfate
US Patents:5,585,343 - Low VOC perfume formulations
PubMed:Effects of buffered vinegar and sodium dodecyl sulfate plus levulinic acid on Salmonella Typhimurium survival, shelf-life, and sensory characteristics of ground beef patties.
PubMed:Characterization and modeling of the interactions between coffee storage proteins and phenolic compounds.
PubMed:Measuring local equilibrium flavor distributions in SDS solution using headspace solid-phase microextraction.
PubMed:Proteolytic activity of lactic acid bacteria strains and fungal biota for potential use as starter cultures in dry-cured ham.
PubMed:Wheat bran stabilization and its use in the preparation of high-fiber pasta.
PubMed:Influence of droplet charge on the chemical stability of citral in oil-in-water emulsions.
PubMed:One-step purification and characterization of a beta-1,4-glucosidase from a newly isolated strain of Stereum hirsutum.
PubMed:Genotypic identification of some lactic acid bacteria by amplified fragment length polymorphism analysis and investigation of their potential usage as starter culture combinations in Beyaz cheese manufacture.
PubMed:Interaction of copper and human salivary proteins.
PubMed:In vitro determination of the allergenic potential of technologically altered hen's egg.
PubMed:Chemical and physical stability of citral and limonene in sodium dodecyl sulfate-chitosan and gum arabic-stabilized oil-in-water emulsions.
PubMed:Purification and characterization of an extracellular protease from Penicillium chrysogenum Pg222 active against meat proteins.
PubMed:Isolation and characterization of a peanut maturity-associated protein.
PubMed:Purification, characterization, and substrate specificity of a novel highly glucose-tolerant beta-glucosidase from Aspergillus oryzae.
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