| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 122-99-6 |
| ECHA EC Number: | 204-589-7 |
| FDA UNII: | HIE492ZZ3T |
| Category: | flavor and fragrance agents |
| IUPAC Name: | phenoxyethanol |
| InChI : | InChI=1/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2 |
| Std.InChI: | InChI=1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2 |
| InChIKey : | QCDWFXQBSFUVSP-UHFFFAOYAU |
| Std.InChIKey: | QCDWFXQBSFUVSP-UHFFFAOYSA-N |
| SMILES : | C1=CC=C(C=C1)OCCO |
| MDL: | MFCD00002857 |
| Molar Refractivity : | 39.09 ± 0.3 cm3 (est) |
| Parachor : | 320.4 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.525 ± 0.02 (est) |
| Surface Tension : | 39.9 ± 3.0 dyne/cm (est) |
| Density : | 1.084 ± 0.06 g/cm3 (est) |
| Polarizability : | 15.50 ± 0.5 10-24cm3 (est) |
| Fragrance Demo Formulas | |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FEMA Number: | 4620 2-phenoxyethanol |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 122-99-6 ; ETHYLENE GLYCOL MONOPHENYL ETHER |
| FDA Mainterm (IAUFC): | 122-99-6 ; ETHYLENE GLYCOL MONOPHENYL ETHER |
| Appearance: | colorless oily liquid to solid (exp) |
| Assay: | 95.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.10500 to 1.10800 @ 25.00 °C. |
| Pounds per Gallon - (est).: | 9.195 to 9.220 |
| Refractive Index: | 1.53700 to 1.54000 @ 20.00 °C. |
| Melting Point: | 12.00 to 14.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 237.00 to 238.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 153.00 to 154.00 °C. @ 50.00 mm Hg |
| Vapor Pressure: | 0.016000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 250.00 °F. TCC ( 121.11 °C. ) |
| logP (o/w): | 1.160 |
| Soluble in: | |
| alcohol | |
| paraffin oil, slightly soluble | |
| water, 26700 mg/L @ 20 °C (exp) | |
| Insoluble in: | |
| water | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | preservatives |
| Acme-Hardesty |
| Phenoxyethanol Odor: characteristic Use: High Performance, Broad Spectrum Preservative for Cosmetics and Personal Care Products. |
| American International Chemical, LLC. |
| PHENOXYETHANOL |
| American International Chemical, LLC. |
| PURECARE PB 81 |
| American International Chemical, LLC. |
| PURECARE PB 82 |
| American International Chemical, LLC. |
| PURECARE PB 83 |
| Augustus Oils |
| Phenoxy Ethanol |
| Services |
| Berjé |
| Phenoxy Ethanol (Rose Ether) |
| Media |
| BOC Sciences |
| For experimental / research use only. |
| 2-Phenoxyethanol >98.5%(GC) |
| Charkit Chemical |
| PHENOXYETHANOL 99% |
| Connect Chemicals |
| Phenoxyethanol Odor: characteristic Use: Preservation of cosmetics, toiletry and household products and their raw materials. Phenoxyethanol is often used in combination with other active substances. In some cases positive synergetic effects can be obtained. It is used in acne treatment. Due to its low evaporation, Phenoxyethanol is used as a fixative in perfumes and fragrance. |
| ECSA Chemicals |
| PHENOXYETHANOL PH EUR |
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| ECSA Chemicals |
| PHENOXYETHANOL |
| HallStar |
| CoSept(tm) PEP Odor: characteristic Use: CoSept PEP is a broad-spectrum preservative with ingredients approved for use in many countries. It is compatible with the vast majority of raw materials used in cosmetic and personal care products (highly ethoxylated compounds may reduce efficacy). It is a clear, thin, colorless to light straw-colored solution of five parabens in phenoxyethanol. The phenoxyethanol imparts a slight “rose essence” aroma to the product.As a mobile liquid, CoSept PEP can be easily incorporated without high temperature processing. Nonetheless, it is essentially nonvolatile and is not adversely affected by typical hot processing (up to 85°C) conditions. Due to the limited water solubility of its ingredients, addition to the oil phase (or to a water phase after addition of surfactants) will promote solution. Addition to the water phase optimizes initial antimicrobial activity, as parabens will tend to migrate into an oil phase with time. CoSept PEP is optimally effective at acidic to neutral pH, and is recommended for use over the pH range of 3 to 8. Typical use levels range from 0.3 to 1.0% wt. |
| Indukern F&F |
| PHENOXYETHYL ALCOHOL Odor: FLORAL, FRESH, ROSE |
| Jiangyin Healthway |
| Phenoxyethanol |
| New functional food ingredients |
| Jiangyin Healthway |
| Phenoxyethanol |
| Kingyoung Bio Technical |
| Phenoxyethanol |
| Kraft Chemical |
| Phenoxyethanol |
| Lluch Essence |
| PHENOXYETHYL ALCOHOL |
| Moellhausen |
| PHENOXYETHYL ALCOHOL Odor: fresh, floreal, rose note Flavor: aromatic, floral, somewhat phenolic |
| OQEMA |
| LanCos PR POE |
| Penta International |
| 2-PHENOXYETHANOL NF/BP GRADE |
| Penta International |
| 2-PHENOXYETHANOL NF/EP GRADE |
| Penta International |
| 2-PHENOXYETHANOL USP - NF |
| Penta International |
| 2-PHENOXYETHANOL |
| Prasad Organics |
| Rose Ether |
| Prodasynth |
| PHENOXYETHYLIC ALCOHOL (> 96%) |
| Sarchem Laboratories |
| For experimental / research use only. |
| Phenoxyethanol |
| Sigma-Aldrich |
| For experimental / research use only. |
| 2-Phenoxyethanol ≥99.0% |
| Silver Fern Chemical |
| Glycol Ether EPh Odor: characteristic Use: Glycol Ether EPh has a wide range of applications including personal care products, water-based coatings, as a solvent for plasticizers, resins, and inks, an emulsifier, corrosion inhibitor, bactericidal agent, pharmaceuticals, germicides, perfume fixatives, and insect repellents. |
| Spec-Chem Industry |
| ParbFree TM PCG |
| Symrise |
| Phenoxyethyl alcohol Odor: weak, mild, rosy, balsamic, cinnamon-like, fixative and solvent |
| Symrise |
| SymOcide® PS Odor: characteristic Use: SymOcide® PS, a broad-spectrum preservative system, is a synergistic blend of Phenoxyethanol and 1,2-Alkanediols, that can be used to preserve a multitude of cosmetic applications as it works in leave-on products as well as rinse-off products. New data confirm that SymOcide® PS is able to stabilize emulsions and to work as an efficient deodorant for 24 hours protection. All components of SymOcide® PS are listed in 2004 CTFA/PCPC ingredients. |
| Symrise |
| SymOcide® PT Life Essentials - Actives Odor: characteristic Use: SymOcide® PT is a synergistic blend of Phenoxyethanol (a preservative) and Tropolone. It is a colorless to pale yellow liquid with a mild characteristic odor. SymOcide® PT is highly effective against micro-organisms. SymOcide® PT can be used against gram-positive and gram-negative organisms. The synergistic effect of this product offers a wide spectrum of protection. |
| Synerzine |
| 2-Phenoxy Ethanol |
| SysKem Chemie |
| Phenoxy Ethanol |
| TCI AMERICA |
| For experimental / research use only. |
| 2-Phenoxyethanol >98.5%(GC) |
| The John D. Walsh Company |
| Phenoxy Ethanol |
| TRI-K Industries |
| TRIstat P5 Odor: characteristic Use: A paraben and formaldehyde free cosmetic preservative. It is a high purity grade suitable for pharmaceutical applications. |
| TRI-K Industries |
| TRIstat PR Odor: characteristic Use: A paraben-free, formaldehyde-free cosmetic preservative. |
| Universal Preserv-A-Chem Inc. |
| PHENOXYETHANOL |
| Vevy Europe |
| UNDEBENZOFENE-C P-F Odor: characteristic Use: Preservative having broad action spectrum (gram +/- bacteria, particularly Pseudomonas aeruginosa; molds, yeasts and fungi). Compatible with usual cosmetic ingredients. |
| Vevy Europe |
| UNDEBENZOFENE-C Odor: characteristic Use: Preservative with a broad bactericide spectrum (Gram +/-) and particularly pseudomonicide; anti-mildew, anti-yeast; non-irritant for human tissues. Insect repellent. Synergic action with quaternary ammonium salts. Compatible with Alutrat (Vevy codex 12.0250) and Laurene (Vevy codex 11.0496), ionic and non-ionic agents. Chemically inert in the presence of essential oils and perfumes. |
| Vigon International |
| Phenoxy Ethanol 99% (Rose Ether) Odor: Weak, mild, rosy, balsamic, cinnamon-like |
| Vigon International |
| SymOcide PS (Phenoxy Ethanol, 1,2 Hexanediol, Decylene Glycol) |
| Vigon International |
| SYMOCIDE® PH |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xn - Harmful. | |
| R 22 - Harmful if swallowed. R 36 - Irritating to eyes. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37 - Wear suitable gloves. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 1260 mg/kg BEHAVIORAL: GENERAL ANESTHETICGASTROINTESTINAL: OTHER CHANGESKIDNEY, URETER, AND BLADDER: OTHER CHANGES Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941. intraperitoneal-mouse LD50 490 mg/kg BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. oral-mouse LD50 933 mg/kg BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. intraperitoneal-rat LD50 554 mg/kg BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 5 ml/kg Union Carbide Data Sheet. Vol. 6/24/1958 skin-rat LD50 14422 mg/kg LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Journal of the American College of Toxicology. Vol. 9, Pg. 259, 1990. | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| flavor and fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for phenoxyethanol usage levels up to: | |||
| 5.0000 % in the fragrance concentrate. | |||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 24 | |||
| Click here to view publication 24 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 4.00000 | 8.00000 | |
| beverages(nonalcoholic): | 0.50000 | 2.00000 | |
| beverages(alcoholic): | 1.00000 | 3.00000 | |
| breakfast cereal: | - | - | |
| cheese: | - | - | |
| chewing gum: | - | - | |
| condiments / relishes: | - | - | |
| confectionery froastings: | - | - | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | 2.00000 | 5.00000 | |
| fruit ices: | 1.00000 | 2.00000 | |
| gelatins / puddings: | 1.00000 | 3.00000 | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | 1.00000 | 5.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | - | - | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | 1.00000 | 5.00000 | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):122-99-6 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :31236 |
| National Institute of Allergy and Infectious Diseases:Data |
| SCCNFP:opinion |
| WGK Germany:1 |
| 2-phenoxyethanol |
| Chemidplus:0000122996 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:122-99-6 |
| 2-phenoxyethanol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 122-99-6 |
| Pubchem (cid): | 31236 |
| Pubchem (sid): | 134974207 |
| Pherobase: | View |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | D08359 |
| HMDB (The Human Metabolome Database): | HMDB41607 |
| FooDB: | FDB021762 |
| YMDB (Yeast Metabolome Database): | YMDB01591 |
| Export Tariff Code: | 2909.50.5000 |
| Typical G.C. | |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| Formulations/Preparations: grade: technical | |
| FR | acacia |
| FR | aldehydic |
| FR | almond |
| FR | amber |
| FR | ambrene |
| FR | angel essence |
| antibacterial agents | |
| FR | apple blossom |
| FR | apricot |
| FR | balsam |
| bellodgia | |
| FR | blue grass |
| FR | blue mist |
| FR | bluebell |
| FR | blueberry |
| FR | botanical |
| FR | bouquet |
| FR | carnation |
| FR | champaca |
| FR | cherry |
| FR | cherry blossom |
| FR | chestnut blossom |
| FR | civet |
| FR | coconut tropical coconut |
| FR | country meadow |
| FR | crabapple blossom |
| FR | currant |
| FR | elder berry |
| FR | fern |
| FR | fetes |
| fixer | |
| FR | floral |
| FR | frangipani plumeria |
| FR | gardenia |
| FR | genet |
| FR | geranium |
| FR | ginger white ginger |
| FR | gooseberry |
| FR | hawthorn |
| FR | heather |
| FR | heliotrope |
| FR | herbal |
| FR | hibiscus |
| FR | honeysuckle |
| FR | hop |
| FR | hyacinth |
| FR | jasmin |
| FR | jonquil |
| FR | kiwi blossom |
| FR | leather |
| FR | lemon |
| FR | lilac |
| FR | lily |
| FR | lily of the valley |
| FR | linden flower |
| FR | lotus |
| FR | magnolia |
| FR | mulberry |
| FR | narcissus |
| FR | neroli |
| FR | orange blossom |
| FR | orchid |
| FR | oriental |
| FR | orris |
| FR | peach |
| FR | peony |
| FR | potpourri |
| FR | powder |
| preservatives | |
| quelques fleurs | |
| FR | rain |
| FR | raspberry |
| FR | rose |
| FL/FR | rose leaf |
| FR | rose red rose |
| FR | rose tea rose |
| FR | rose white rose |
| FR | sandalwood |
| FR | spice |
| FR | strawberry |
| FR | sweet pea |
| FL | tea black tea |
| FR | tea green tea |
| FR | tuberose |
| FR | violet |
| FR | wallflower |
| FR | woody |
| FR | ylang ylang |
| 1160 rose ether | |
| alcool phenoxyethylique | |
| arosol | |
| cosept PEP | |
| dowanol EP | |
| emeressence 1160 rose ether | |
| ethanol, 2-phenoxy- | |
| ethylene glycol monophenyl ether | |
| ethylene glycol phenyl ether | |
| glycol monophenyl ether | |
| 1- | hydroxy-2-phenoxyethane |
| 2- | hydroxyethyl phenyl ether |
| beta- | hydroxyethyl phenyl ether |
| igepal OD 410 | |
| phenoxetol | |
| phenoxy ethanol | |
| phenoxy ethanol (rose ether) | |
| 2-( | phenoxy)ethanol |
| 2- | phenoxy-ethanol |
| 2- | phenoxyethan-1-ol |
| 2- | phenoxyethanol |
| beta- | phenoxyethanol |
| 2- | phenoxyethanol NF/BP grade |
| 2- | phenoxyethanol NF/EP grade |
| phenoxyethyl alcohol | |
| phenoxytol | |
| phenyl cellosolve | |
| phenyl monoglycol ether | |
| phenylglycol | |
| rose ether | |
| rose ether 1160 | |
| symocide PS (phenoxy ethanol, 1,2 hexanediol, decylene glycol) | |
| symocide PS (Symrise) | |
| symocide PT (Symrise) | |
| tristat P5 | |
| undebenzofene-C (Vevy) | |
| undebenzofene-C P-F (Vevy) |
