| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 118-55-8 |
| ECHA EC Number: | 204-259-2 |
| FDA UNII: | 28A37T47QO |
| CoE Number: | 11814 |
| Category: | antimicrobial agents |
| IUPAC Name: | phenyl salicylate |
| InChI : | InChI=1/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H |
| Std.InChI: | InChI=1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H |
| InChIKey : | ZQBAKBUEJOMQEX-UHFFFAOYAI |
| Std.InChIKey: | ZQBAKBUEJOMQEX-UHFFFAOYSA-N |
| SMILES : | C1=CC=C(C=C1)OC(=O)C2=CC=CC=C2O |
| MDL: | MFCD00002213 |
| Molar Refractivity : | 59.77 ± 0.3 cm3 (est) |
| Parachor : | 459.6 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.615 ± 0.02 (est) |
| Surface Tension : | 51.8 ± 3.0 dyne/cm (est) |
| Density : | 1.250 ± 0.06 g/cm3 (est) |
| Polarizability : | 23.69 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| JECFA Food Flavoring: | 736 phenyl salicylate |
| DG SANTE Food Flavourings: | 09.689 phenyl salicylate |
| FEMA Number: | 3960 phenyl salicylate |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 118-55-8 ; PHENYL SALICYLATE |
| FDA Regulation: | |
| FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1010 Acrylic and modified acrylic plastics, semirigid and rigid. | |
| Berjé |
| Phenyl Salicylate |
| Media |
| BOC Sciences |
| For experimental / research use only. |
| Phenyl Salicylate |
| Fleurchem |
| phenyl salicylate |
| Penta International |
| PHENYL SALICYLATE |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Phenyl Salicylate |
| Sigma-Aldrich |
| Phenyl salicylate, ≥99%, FG |
| Certified Food Grade Products |
| TCI AMERICA |
| For experimental / research use only. |
| Phenyl Salicylate >98.0%(GC) |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
| R 36/38 - Irritating to skin and eyes. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 3000 mg/kg Food and Cosmetics Toxicology. Vol. 14, Pg. 837, 1976. intraperitoneal-mouse LD > 500 mg/kg "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 149, 1954. oral-rabbit LDLo 3000 mg/kg SENSE ORGANS AND SPECIAL SENSES: OTHER: EYEBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Revue Medicale de la Suisse Romande. Vol. 15, Pg. 561, 1895. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| antimicrobial agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| maximum skin levels for fine fragrances: | |||
| 0.0200 % and are based on the assumption that the fragrance mixture is used at 20% in a consumer product (IFRA Use Level Survey). | |||
| Recommendation for phenyl salicylate usage levels up to: | |||
| 2.0000 % in the fragrance concentrate. | |||
| use level in formulae for use in cosmetics: | |||
| 0.0200 % | |||
| Dermal Systemic Exposure in Cosmetic Products: | |||
| 0.0005 mg/kg/day | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 7.30 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 8.00 (μg/capita/day) | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 19 | |||
| Click here to view publication 19 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 40.00000 | 100.00000 | |
| beverages(nonalcoholic): | 40.00000 | 100.00000 | |
| beverages(alcoholic): | 40.00000 | 100.00000 | |
| breakfast cereal: | 40.00000 | 100.00000 | |
| cheese: | - | - | |
| chewing gum: | 400.00000 | 1200.00000 | |
| condiments / relishes: | - | - | |
| confectionery froastings: | 40.00000 | 100.00000 | |
| egg products: | - | - | |
| fats / oils: | - | - | |
| fish products: | - | - | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | - | - | |
| hard candy: | 40.00000 | 100.00000 | |
| imitation dairy: | - | - | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | - | - | |
| milk products: | 40.00000 | 100.00000 | |
| nut products: | - | - | |
| other grains: | - | - | |
| poultry: | - | - | |
| processed fruits: | - | - | |
| processed vegetables: | - | - | |
| reconstituted vegetables: | - | - | |
| seasonings / flavors: | - | - | |
| snack foods: | - | - | |
| soft candy: | 40.00000 | 100.00000 | |
| soups: | - | - | |
| sugar substitutes: | - | - | |
| sweet sauces: | - | - | |
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Flavouring Group Evaluation 88, (FGE.88)[1] - Consideration of Phenol and Phenol Derivatives - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food View page or View pdf |
| EPI System: View |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):118-55-8 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :8361 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| phenyl 2-hydroxybenzoate |
| Chemidplus:0000118558 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:VO6125000 for cas# 118-55-8 |
| phenyl 2-hydroxybenzoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 118-55-8 |
| Pubchem (cid): | 8361 |
| Pubchem (sid): | 134973877 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C14163 |
| HMDB (The Human Metabolome Database): | HMDB32018 |
| FooDB: | FDB008716 |
| Export Tariff Code: | 2918.23.5000 |
| ChemSpider: | View |
| Wikipedia: | View |
| antimicrobial agents | |
| FR | balsam |
| denaturants | |
| FR | fruit |
| FR | herbal |
| intensifier | |
| FR | wintergreen |
| not found in nature |
| benzoic acid, 2-hydroxy-, phenyl ester | |
| 2- | hydroxybenzoic acid phenyl ester |
| 2- | hydroxybenzoic acid, phenyl ester |
| musol | |
| phenol salicylate | |
| 2- | phenoxycarbonyl phenol |
| 2- | phenoxycarbonylphenol |
| phenyl 2-hydroxybenzoate | |
| phenyl-alpha-hydroxybenzoate | |
| salicylic acid phenyl ester | |
| salicylic acid, phenyl ester | |
| salol | |
| salphenyl | |
| seesorb 201 | |
| seesorb K 201 |
