| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 111-46-6 |
| ECHA EC Number: | 203-872-2 |
| FDA UNII: | 61BR964293 |
| Category: | solvents |
| IUPAC Name: | diethylene glycol |
| InChI : | InChI=1/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2 |
| Std.InChI: | InChI=1S/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2 |
| InChIKey : | MTHSVFCYNBDYFN-UHFFFAOYAK |
| Std.InChIKey: | MTHSVFCYNBDYFN-UHFFFAOYSA-N |
| SMILES : | C(COCCO)O |
| MDL: | MFCD00002882 |
| Molar Refractivity : | 25.39 ± 0.3 cm3 (est) |
| Parachor : | 244.4 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.442 ± 0.02 (est) |
| Surface Tension : | 42.1 ± 3.0 dyne/cm (est) |
| Density : | 1.106 ± 0.06 g/cm3 (est) |
| Polarizability : | 10.06 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| FCN 1832 | Diethylene glycol View - notice |
| DG SANTE Food Contact Materials: | diethylene glycol |
| FDA Mainterm (IAUFC): | 111-46-6 ; DIETHYLENE GLYCOL |
| FDA Regulation: | |
| FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart B--Substances for Use Only as Components of Adhesives Sec. 175.105 Adhesives. | |
| Appearance: | colorless clear oily liquid (est) |
| Assay: | 95.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.11800 @ 25.00 °C. |
| Melting Point: | -6.50 °C. @ 760.00 mm Hg |
| Boiling Point: | 244.00 to 246.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.005700 mmHg @ 25.00 °C. |
| Vapor Density: | 3.66 ( Air = 1 ) |
| Flash Point: | 290.00 °F. TCC ( 143.33 °C. ) |
| logP (o/w): | 1.470 (est) |
| Soluble in: | |
| water, 1000000 mg/L @ 25 °C (exp) | |
| alcohol | |
| ether | |
| acetone | |
| ethylene glycol | |
| Insoluble in: | |
| benzene | |
| toluene | |
| carbon tetrachloride | |
| AquaChemie |
| For experimental / research use only. |
| Di Ethylene Glycol- DEG |
| BOC Sciences |
| For experimental / research use only. |
| Diglycol N/A |
| ECSA Chemicals |
| DIETHYLENE GLYCOL |
| ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY |
| Glentham Life Sciences |
| Diethylene glycol |
| Penta International |
| DIETHYLENE GLYCOL |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Diethylene Glycol 99% |
| Shiva Chemicals and Pharmaceuticals |
| Diethylene Glycol |
| Sigma-Aldrich |
| For experimental / research use only. |
| Diethylene glycol puriss. p.a., ≥99.0% (GC), colorless |
| Silver Fern Chemical |
| Diethylene Glycol (DEG) Odor: characteristic Use: DEG is a widely used solvent. It is used in the manufacture of resins, polyurethanes, plasticizers, and is also used as a solvent for dyes and oils. DEG can be found in products such as tobacco, cork, ink, glue, brake fluid, lubricants, and cosmetics. |
| Wedor Corporation |
| DIETHYLENE GLYCOL |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 12565 mg/kg Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 25, 1974. oral-rabbit LD50 4400 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEABEHAVIORAL: COMA Journal of Industrial Hygiene and Toxicology. Vol. 21, Pg. 173, 1939. oral-cat LD50 3300 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 21, Pg. 173, 1939. oral-child TDLo 2400 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)LIVER: OTHER CHANGES Journal of Pediatrics. Vol. 109, Pg. 731, 1986. oral-dog LD50 9000 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 67, Pg. 101, 1939. oral-guinea pig LD50 7800 mg/kg LIVER: OTHER CHANGESBEHAVIORAL: GENERAL ANESTHETICBEHAVIORAL: MUSCLE WEAKNESS Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945. unreported-guinea pig LD50 14000 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: EXCITEMENT Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. oral-human LDLo 1000 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 21, Pg. 173, 1939. intraperitoneal-mouse LD50 9719 mg/kg BLOOD: CHANGES IN SPLEENKIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULILUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947. oral-mouse LD50 23700 mg/kg BEHAVIORAL: MUSCLE WEAKNESSBEHAVIORAL: GENERAL ANESTHETICLIVER: OTHER CHANGES Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 4, Pg. 142, 1945. unreported-mouse LD50 13300 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: EXCITEMENTGASTROINTESTINAL: NAUSEA OR VOMITING Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. unreported-rabbit LD50 2688 mg/kg BEHAVIORAL: EXCITEMENTGASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. intramuscular-rabbit LDLo 4472 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 59, Pg. 93, 1937. intravenous-rabbit LDLo 2236 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 59, Pg. 93, 1937. intraperitoneal-rat LD50 7700 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3836, 1982. intravenous-rat LD50 6565 mg/kg Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 25, 1974. unreported-rat LD50 15650 mg/kg BEHAVIORAL: EXCITEMENTBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)GASTROINTESTINAL: NAUSEA OR VOMITING Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(3), Pg. 16, 1968. intramuscular-rat LDLo 7826 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 59, Pg. 93, 1937. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 11890 mg/kg Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 25, 1974. subcutaneous-rat LD50 18800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed.,1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. i subcutaneous-mouse LDLo 5000 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 42, Pg. 355, 1931. subcutaneous-rat LD50 18800 mg/kg "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3836, 1982. | |
| Inhalation Toxicity: | |
| inhalation-mouse LCLo 130 mg/m3/2H LUNGS, THORAX, OR RESPIRATION: CYANOSISBEHAVIORAL: EXCITEMENTBEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 10(12), Pg. 30, 1966. | |
| Category: | |||
| solvents | |||
| Recommendation for diethylene glycol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for diethylene glycol flavor usage levels up to: | |||
| not for flavor use. | |||
| European Food Safety Authority (EFSA) reference(s): |
| Safety of the proposed amendment of the specifications for the food additive polyvinyl alcohol-polyethylene glycol-graft-co-polymer (E 1209) View page or View pdf |
| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA Substance Registry Services (TSCA):111-46-6 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :8117 |
| National Institute of Allergy and Infectious Diseases:Data |
| SCCNFP:opinion |
| WGK Germany:1 |
| 2-(2-hydroxyethoxy)ethanol |
| Chemidplus:0000111466 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:111-46-6 |
| 2-(2-hydroxyethoxy)ethanol | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 111-46-6 |
| Pubchem (cid): | 8117 |
| Pubchem (sid): | 134975028 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C14689 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2909.41.0000 |
| Wikipedia: | View |
| None Found |
| None Found |
| not found in nature |
| brecolane NDG | |
| deactivator E | |
| deg | |
| di(ethylene glycol) | |
| 2,2- | di(hydroxyethyl) ether |
| dicol | |
| 2,2'-oxy | diethanol |
| diglycol | |
| 1,5- | dihydroxy-3-oxapentane |
| dihydroxydiethyl ether | |
| 2,2'- | dihydroxydiethyl ether |
| beta,beta'- | dihydroxydiethyl ether |
| 2,2'- | dihydroxyethyl ether |
| dissolvant APV | |
| 2,2'-oxy | ethanol |
| 2,2'-oxybis | ethanol |
| 2,2'-oxybis[ | ethanol] |
| 2-(2- | hydroxyethoxy)ethanol |
| 2- | hydroxyethyl ether |
| 3-oxa-1,5- | pentane diol |
| 3-oxa | pentane-1,5-diol |
| tl4n |
| None found yet. Try the PubMed Search. |
