| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 109-29-5 |
| ECHA EC Number: | 203-662-0 |
| FDA UNII: | 64E2HO00C7 |
| Category: | flavor and fragrance agents |
| IUPAC Name: | juniper lactone |
| InChI : | InChI=1/C16H30O2/c17-16-14-12-10-8-6-4-2-1-3-5-7-9-11-13-15-18-16/h1-15H2 |
| Std.InChI: | InChI=1S/C16H30O2/c17-16-14-12-10-8-6-4-2-1-3-5-7-9-11-13-15-18-16/h1-15H2 |
| InChIKey : | LOKPJYNMYCVCRM-UHFFFAOYAX |
| Std.InChIKey: | LOKPJYNMYCVCRM-UHFFFAOYSA-N |
| SMILES : | C1CCCCCCCC(=O)OCCCCCCC1 |
| MDL: | MFCD00039668 |
| Molar Refractivity : | 75.52 ± 0.3 cm3 (est) |
| Parachor : | 666.9 ± 6.0 cm3 (est) |
| Index of Refraction : | 1.435 ± 0.02 (est) |
| Surface Tension : | 28.3 ± 3.0 dyne/cm (est) |
| Density : | 0.879 ± 0.06 g/cm3 (est) |
| Polarizability : | 29.93 ± 0.5 10-24cm3 (est) |
| Fragrance Demo Formulas | |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| DG SANTE Food Flavourings: | 10.047 hexadecano-1,16-lactone |
| Appearance: | colorless solid (est) |
| Assay: | 95.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Refractive Index: | 1.46800 to 1.47300 @ 20.00 °C. |
| Melting Point: | 34.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 358.13 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure: | 0.000026 mmHg @ 25.00 °C. (est) |
| Flash Point: | > 212.00 °F. TCC ( > 100.00 °C. ) |
| logP (o/w): | 6.650 |
| Shelf Life: | 36.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: | |
| alcohol | |
| water, 0.04727 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | fragrance perfuming agents |
| ACS International |
| Dihydroambrettolide Extra Pure Odor: sweet musk balsamic amber |
| Operational Capabilities |
| ACS International |
| Dihydroambrettolide Odor: sweet musk balsamic amber |
| Associate Allied Chemicals |
| Dihydro Ambrettolide BM |
| About |
| Associate Allied Chemicals |
| Hexadecanolide |
| Azelis UK |
| HEXADECANOLIDE |
| BOC Sciences |
| For experimental / research use only. |
| 16-HEXADECANOLIDE 95% |
| CJ Latta & Associates |
| DIHYDRO AMBRETTOLIDE |
| Ernesto Ventós |
| DIHYDROAMBRETTOLIDE SYNAROME Odor: MUSK,SWEET,ANIMAL,BALSAMIC |
| Ernesto Ventós |
| HEXADECANOLIDE IFF Odor: MUSK,SWEET,ANIMAL,BALSAMIC |
| IFF |
| Hexadecanolide Odor: Sweet musk note of great diffusion and tenacity with balsamic, animal effects |
| Indukern F&F |
| HEXADECANOLIDE Odor: MUSK, SWEET, BALSAMIC, ANIMAL |
| Liaison Carbone |
| HEXADECANOLIDE |
| Lluch Essence |
| CYCLOHEXADECANOLIDE Odor: MUSKY, ANIMALIC, SWEET |
| M&U International |
| Hexadecanolide(IFF# : 00082663) |
| Moellhausen |
| HEXADECANOLIDE DIHYDROAMBRETTOLIDE |
| Pell Wall Perfumes |
| Dihydroambrettolide Odor: Musk, animalic, sweet, ambery, balsamic. Radiant and excellent fixative Use: Arctander says "DHA finds still some application in perfume compositions as a fixative with clean musky, slightly animal and foral undertones, and excellent performance in alcoholic solutions, and on the human skin. It may support delicate floral notes as well as typical Ambre notes or discrete Civet/animal tones, and it blends excellently with the purest Methylionones, Vetiver derivatives and aldehyde blends." |
| Penta International |
| HEXADECANOLIDE |
| Sigma-Aldrich |
| For experimental / research use only. |
| 16-Hexadecanolide analytical standard |
| Soda Aromatic |
| Cetanolide |
| Stort Chemicals |
| Dihydroambrettolide |
| Taytonn ASCC |
| Hexadecanolide Odor: Animalic/ Animal, Balsamic, Musk/ Musky, Sweet |
| The John D. Walsh Company |
| Hexadecanolide |
| Tianjin Danjun International |
| Hexadecano-1,16-lactone |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
| R 38 - Irritating to skin. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 452, 1975. | |
| Dermal Toxicity: | |
| skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 13, Pg. 452, 1975. | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| flavor and fragrance agents | |||
| RIFM Fragrance Material Safety Assessment: Search | |||
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice | |||
| Recommendation for juniper lactone usage levels up to: | |||
| 3.0000 % in the fragrance concentrate. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.024 (μg/capita/day) | ||
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 3900 (μg/person/day) | ||
| Threshold of Concern: | 1800 (μg/person/day) | ||
| Structure Class: | I | ||
| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). | |||
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. | |||
| average usage mg/kg | maximum usage mg/kg | ||
| Dairy products, excluding products of category 02.0 (01.0): | 7.00000 | 35.00000 | |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 5.00000 | 25.00000 | |
| Edible ices, including sherbet and sorbet (03.0): | 10.00000 | 50.00000 | |
| Processed fruit (04.1): | 7.00000 | 35.00000 | |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - | |
| Confectionery (05.0): | 10.00000 | 50.00000 | |
| Chewing gum (05.3): | - | - | |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 5.00000 | 25.00000 | |
| Bakery wares (07.0): | 10.00000 | 50.00000 | |
| Meat and meat products, including poultry and game (08.0): | 2.00000 | 10.00000 | |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 2.00000 | 10.00000 | |
| Eggs and egg products (10.0): | - | - | |
| Sweeteners, including honey (11.0): | - | - | |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 5.00000 | 25.00000 | |
| Foodstuffs intended for particular nutritional uses (13.0): | 10.00000 | 50.00000 | |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | 5.00000 | 25.00000 | |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 10.00000 | 50.00000 | |
| Ready-to-eat savouries (15.0): | 20.00000 | 100.00000 | |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 5.00000 | 25.00000 | |
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf |
| Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
| Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab) View page or View pdf |
| Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 10, Revision 3 (FGE.10Rev3): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf |
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):109-29-5 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :7984 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 1-oxacycloheptadecan-2-one |
| Chemidplus:0000109295 |
| RTECS:RN9730000 for cas# 109-29-5 |
| 1-oxacycloheptadecan-2-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 109-29-5 |
| Pubchem (cid): | 7984 |
| Pubchem (sid): | 134973671 |
| Pherobase: | View |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2932.99.9090 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| cetanolide | |
| 1-oxa | cycloheptadecan-2-one |
| oxa | cycloheptadecan-2-one |
| cyclohexadecanolide | |
| cyclohexyl decanolide | |
| dihydro ambrettolide | |
| dihydroambrettolide | |
| dihydroambrettolide (cyclohexadecanolide ) | |
| 1,16- | hexadecalactone |
| hexadecane-16-olide | |
| hexadecano-1,16-lactone | |
| hexadecanoic acid, 16-hydroxy-, .omicron.-lactone | |
| hexadecanoic acid, 16-hydroxy-, omicron-lactone | |
| 1,16- | hexadecanolactone |
| 16- | hexadecanolactone |
| 1,16- | hexadecanolide |
| 16- | hexadecanolide |
| hexadecanolide (IFF) | |
| 16- | hydroxyhexadecanoic acid lactone |
| 16- | hydroxyhexadecanoic acid omicron-lactone |
| 16- | hydroxypalmitic-1,16-olide |
| juniper lactone | |
| juniperic acid lactone | |
| juniperic acid, lactone | |
| juniperlactone |
| None found yet. Try the PubMed Search. |
