| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 107-35-7 |
| ECHA EC Number: | 203-483-8 |
| FDA UNII: | 1EQV5MLY3D |
| CoE Number: | 16056 |
| Category: | special dietary and nutritional additives, also ingredient in enhanced water beverages at a concentration of 45 parts per million |
| IUPAC Name: | taurine |
| InChI : | InChI=1/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6) |
| Std.InChI: | InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6) |
| InChIKey : | XOAAWQZATWQOTB-UHFFFAOYAA |
| Std.InChIKey: | XOAAWQZATWQOTB-UHFFFAOYSA-N |
| SMILES : | C(CS(=O)(=O)O)N |
| MDL: | MFCD00008197 |
| Molar Refractivity : | 25.27 ± 0.4 cm3 (est) |
| Parachor : | 240.6 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.515 ± 0.02 (est) |
| Surface Tension : | 68.1 ± 3.0 dyne/cm (est) |
| Density : | 1.494 ± 0.06 g/cm3 (est) |
| Polarizability : | 10.02 ± 0.5 10-24cm3 (est) |
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Perfumer and Flavorist: | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
| FDA/DG SANTE Petitions, Reviews, Notices: | |
| GRN 586 | Taurine View - notice PDF |
| JECFA Food Flavoring: | 1435 taurine |
| DG SANTE Food Flavourings: | 16.056 taurine |
| FEMA Number: | 3813 taurine |
| FDA: | No longer provide for the use of these seven synthetic flavoring substances |
| FDA Mainterm (SATF): | 107-35-7 ; TAURINE |
| Appearance: | white to pale yellow crystalline solid (est) |
| Assay: | 98.00 to 100.00 |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 301.00 to 303.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 0.000170 mmHg @ 25.00 °C. |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| logP (o/w): | -2.769 (est) |
| Shelf Life: | 24.00 month(s) or longer if stored properly. |
| Storage: | store in cool, dry place in tightly sealed containers, protected from heat and light. |
| Soluble in: | |
| water, 80700 mg/L @ 20 °C (exp) | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | buffering agents |
| Preferred SDS: View | |
| European information : | |
| Most important hazard(s): | |
| Xi - Irritant | |
| R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 24/25 - Avoid contact with skin and eyes. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing. | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| intravenous-rat LD50 > 7000 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)SKIN AND APPENDAGES (SKIN): HAIR: OTHER Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19, Pg. 2671, 1991. oral-mouse LD50 > 7000 mg/kg Drugs in Japan Vol. -, Pg. 51, 1990. intravenous-mouse LD50 > 7000 mg/kg Drugs in Japan Vol. -, Pg. 51, 1990. intraperitoneal-mouse LD50 6630 mg/kg Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 18, Pg. 658, 1983. intravenous-dog LD50 > 2000 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19, Pg. 2677, 1991. oral-mammal (species unspecified) LD > 10000 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 33(10), Pg. 57, 1989. intramuscular-mouse LD50 > 7000 mg/kg Drugs in Japan Vol. -, Pg. 51, 1990. intravenous-rabbit LD50 > 1000 mg/kg Drugs in Japan Vol. -, Pg. 51, 1990. oral-rat LD50 > 5000 mg/kg Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 19, Pg. 2671, 1991. | |
| Dermal Toxicity: | |
| subcutaneous-mouse LD50 6000 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 19, Pg. 48, 1946. | |
| Inhalation Toxicity: | |
| Not determined | |
| Category: | |||
| special dietary and nutritional additives, also ingredient in enhanced water beverages at a concentration of 45 parts per million | |||
| Recommendation for taurine usage levels up to: | |||
| not for fragrance use. | |||
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 770.00 (μg/capita/day) | ||
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 217.00 (μg/capita/day) | ||
| Structure Class: | I | ||
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). | |||
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library | |||
| publication number: 17 | |||
| Click here to view publication 17 | |||
| average usual ppm | average maximum ppm | ||
| baked goods: | 250.00000 | 250.00000 | |
| beverages(nonalcoholic): | 30.00000 | 30.00000 | |
| beverages(alcoholic): | - | - | |
| breakfast cereal: | 1000.00000 | 1000.00000 | |
| cheese: | 630.00000 | 630.00000 | |
| chewing gum: | - | - | |
| condiments / relishes: | 1125.00000 | 1125.00000 | |
| confectionery froastings: | - | - | |
| egg products: | 190.00000 | 190.00000 | |
| fats / oils: | 565.00000 | 565.00000 | |
| fish products: | 190.00000 | 190.00000 | |
| frozen dairy: | - | - | |
| fruit ices: | - | - | |
| gelatins / puddings: | - | - | |
| granulated sugar: | - | - | |
| gravies: | 375.00000 | 375.00000 | |
| hard candy: | - | - | |
| imitation dairy: | 190.00000 | 190.00000 | |
| instant coffee / tea: | - | - | |
| jams / jellies: | - | - | |
| meat products: | 585.00000 | 585.00000 | |
| milk products: | - | - | |
| nut products: | 640.00000 | 640.00000 | |
| other grains: | - | - | |
| poultry: | 550.00000 | 550.00000 | |
| processed fruits: | - | - | |
| processed vegetables: | 200.00000 | 200.00000 | |
| reconstituted vegetables: | 375.00000 | 375.00000 | |
| seasonings / flavors: | 70000.00000 | 70000.00000 | |
| snack foods: | 2100.00000 | 2100.00000 | |
| soft candy: | - | - | |
| soups: | 500.00000 | 500.00000 | |
| sugar substitutes: | 3750.00000 | 3750.00000 | |
| sweet sauces: | 375.00000 | 375.00000 | |
| European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... |
| European Food Safety Authority (EFSA) reference(s): |
| Amino acids from chemical group 34 Flavouring Group Evaluation 26, Revision 1 - Scientific opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf |
| Flavouring Group Evaluation 29 (FGE29)[1] - Substance from the priority list: Vinylbenzene from chemical group 31 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf |
| Flavouring Group Evaluation 79, (FGE.79)[1] - Consideration of amino acids and related substances evaluated by JECFA (63rd meeting) structurally related to amino acids from chemical group 34 evaluated by EFSA in FGE.26Rev1 (2008) View page or View pdf |
| The use of taurine and D-glucurono-gamma-lactone as constituents of the so-called �energy� drinks View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 96 (FGE.96): Consideration of 88 flavouring substances considered by EFSA for which EU production volumes / anticipated production volumes have been submitted on request by DG SANCO. Addendum to FGE. 51, 52, 53, 54, 56, 58, 61, 62, 63, 64, 68, 69, 70, 71, 73, 76, 77, 79, 80, 83, 84, 85 and 87. View page or View pdf |
| Scientific Opinion on the safety and efficacy of taurine as a feed additive for all animal species View page or View pdf |
| Gathering consumption data on specific consumer groups of energy drinks View page or View pdf |
| Scientific Opinion on the safety and efficacy of the use of amino acids (chemical group 34) when used as flavourings for all animal species View page or View pdf |
| Scientific Opinion on the safety of caffeine View page or View pdf |
| Scientific Opinion on Flavouring Group Evaluation 49, Revision 1 (FGE.49Rev1): xanthine alkaloids from the priority list View page or View pdf |
| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA Substance Registry Services (TSCA):107-35-7 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :1123 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 2-aminoethanesulfonic acid |
| Chemidplus:0000107357 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:WX0175000 for cas# 107-35-7 |
| 2-aminoethanesulfonic acid | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 107-35-7 |
| Pubchem (cid): | 1123 |
| Pubchem (sid): | 134972418 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| CHEBI: | View |
| CHEMBL: | View |
| Metabolomics Database: | Search |
| KEGG (GenomeNet): | C00245 |
| HMDB (The Human Metabolome Database): | HMDB00251 |
| FooDB: | FDB003191 |
| YMDB (Yeast Metabolome Database): | YMDB00772 |
| Export Tariff Code: | 2921.19.6190 |
| FDA Listing of Food Additive Status: | View |
| MedlinePlusSupp: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
| None Found |
| None Found |
| 2- | aminoetahanesulfonic acid |
| 2- | aminoethane sulfonic acid |
| 2- | aminoethane-1-sulfonic acid |
| 1- | aminoethane-2-sulfonic acid |
| 2- | aminoethanesulfonic acid |
| 2- | aminoethanesulphonic acid |
| 2- | aminoethyl sulfonic acid |
| beta- | aminoethyl sulfonic acid |
| .beta.- | aminoethylsulfonic acid |
| 2- | aminoethylsulfonic acid |
| b- | aminoethylsulfonic acid |
| ethanesulfonic acid, 2-amino- | |
| ethanesulfonic acid, 2-amino- (9CI) | |
| 2- | sulfoethyl amine |
| taukard | |
| tauphon | |
| taurine (8CI) | |
| taurine [INN] |
