| 2D: |  |
|---|---|
| 3D: | |
| CAS Number: | 107-06-2 |
| ECHA EC Number: | 203-458-1 |
| FDA UNII: | 55163IJI47 |
| Category: | extraction solvents |
| IUPAC Name: | 1,2-dichloroethane |
| InChI : | InChI=1/C2H4Cl2/c3-1-2-4/h1-2H2 |
| Std.InChI: | InChI=1S/C2H4Cl2/c3-1-2-4/h1-2H2 |
| InChIKey : | WSLDOOZREJYCGB-UHFFFAOYAL |
| Std.InChIKey: | WSLDOOZREJYCGB-UHFFFAOYSA-N |
| SMILES : | C(CCl)Cl |
| MDL: | MFCD00000963 |
| Molar Refractivity : | 21.01 ± 0.3 cm3 (est) |
| Parachor : | 188.6 ± 4.0 cm3 (est) |
| Index of Refraction : | 1.412 ± 0.02 (est) |
| Surface Tension : | 25.0 ± 3.0 dyne/cm (est) |
| Density : | 1.173 ± 0.06 g/cm3 (est) |
| Polarizability : | 8.33 ± 0.5 10-24cm3 (est) |
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.25600 @ 25.00 °C. |
| Boiling Point: | 83.00 to 84.00 °C. @ 760.00 mm Hg |
| Vapor Pressure: | 78.900000 mmHg @ 25.00 °C. |
| Flash Point: | 60.00 °F. TCC ( 15.56 °C. ) |
| logP (o/w): | 1.480 |
| Soluble in: | |
| water, 8600 mg/L @ 25 °C (exp) | |
| CosIng: | cosmetic data |
| Cosmetic Uses: | not used anymore |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| oral-rat LD50 670 mg/kg Farm Chemicals Handbook. Vol. -, Pg. C130, 1991. oral-dog LD50 5700 mg/kg BEHAVIORAL: GENERAL ANESTHETICBEHAVIORAL: ATAXIASENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970. intravenous-dog LDLo 175 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. intraperitoneal-guinea pig LDLo 600 mg/kg American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974. oral-human LDLo 286 mg/kg LIVER: FATTY LIVER DEGERATIONGASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH Casopis Lekaru Ceskych. Journal of Czech Physicians. Vol. 86, Pg. 203, 1947. oral-human TDLo 428 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITINGLUNGS, THORAX, OR RESPIRATION: COUGHBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Sovetskaia Meditsina. Vol. 22(10), Pg. 132, 1958. oral-man LDLo 714 mg/kg LUNGS, THORAX, OR RESPIRATION: CYANOSISBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)CARDIAC: CHANGE IN RATE Klinische Wochenscrift. Vol. 48, Pg. 822, 1970. oral-man TDLo 892 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITINGLIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Wiadomosci Lekarskie. Medical News. Vol. 28, Pg. 983, 1975. intraperitoneal-mouse LD50 470 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 902, 1961. oral-mouse LD50 413 mg/kg LIVER: OTHER CHANGESLUNGS, THORAX, OR RESPIRATION: OTHER CHANGES EHP, Environmental Health Perspectives. Vol. 43, Pg. 41, 1982. oral-rabbit LD50 860 mg/kg Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 264, 1973. intraperitoneal-rat LD50 807 mg/kg Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(4), Pg. 26, 1982. intratracheal-rat LDLo 120 mg/kg National Technical Information Service. Vol. OTS0520615 | |
| Dermal Toxicity: | |
| skin-rabbit LD50 2800 mg/kg BEHAVIORAL: ATAXIASENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYEBEHAVIORAL: GENERAL ANESTHETIC FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970. subcutaneous-mouse LDLo 380 mg/kg Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. subcutaneous-rabbit LDLo 1200 mg/kg Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. subcutaneous-rat LD50 1000 mg/kg BEHAVIORAL: GENERAL ANESTHETICSENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYEBEHAVIORAL: ATAXIA FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970. | |
| Inhalation Toxicity: | |
| inhalation-rat LC50 1000 ppm/7H BEHAVIORAL: COMALUNGS, THORAX, OR RESPIRATION: CYANOSIS AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 482, 1951. inhalation-cat LC > 3000 ppm/7H Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. inhalation-guinea pig LCLo 1500 ppm/7H BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYEKIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. inhalation-mammal (species unspecified) LC > 3000 ppm/7H Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. inhalation-man TCLo 4000 ppm/1H BEHAVIORAL: COMAPERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)GASTROINTESTINAL: NAUSEA OR VOMITING Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 500, 1966. inhalation-mouse LCLo 5000 mg/m3/2H Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 141, Pg. 19, 1929. inhalation-rabbit LCLo 3000 ppm/7H LUNGS, THORAX, OR RESPIRATION: DYSPNEALUNGS, THORAX, OR RESPIRATION: OTHER CHANGESBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945. | |
| Category: | |||
| extraction solvents | |||
| Recommendation for 1,2-dichloroethane usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for 1,2-dichloroethane flavor usage levels up to: | |||
| not for flavor use. | |||
| EPI System: View |
| EPA-Iris:IRIS |
| NIOSH International Chemical Safety Cards:search |
| NIOSH Pocket Guide:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
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| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):107-06-2 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :11 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 1,2-dichloroethane |
| Chemidplus:0000107062 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:107-06-2 |
| 1,2-dichloroethane | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 107-06-2 |
| Pubchem (cid): | 11 |
| Pubchem (sid): | 134972247 |
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C06752 |
| HMDB (The Human Metabolome Database): | HMDB29571 |
| FooDB: | FDB000726 |
| Export Tariff Code: | 2903.15.0000 |
| FDA Listing of Food Additive Status: | View |
| Wikipedia: | View |
| Formulations/Preparations: •usepaopp pesticide code 042003; trade names: ent-1656; borer sol; brocide; destruxol borer-sol; dichloremulsion; dowfume; dutch liquid; dutch oil; freon 150.•granosan: disinfectant composed of 30% carbon tetrachloride and 70% ethylene dichloride.•grades: technical, spectrophotometric.•ethylene dichloride - carbon tetrachloride (dowfume 75). principal ingredient: 1,2-dichloroethane, commercial formulation, 70% active ingredient; & tetrachloromethane, commercial formulation, 30% active ingredient . | |
| None Found |
| None Found |
| not found in nature |
| 1,2- | bichloroethane |
| alpha,beta- | dichloroethane |
| ethylene dichloride | |
| 1,2- | ethylene dichloride |
| 1,2- | ethylidene dichloride |
| None found yet. Try the PubMed Search. |
