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cyclopentyl amine

information only not used for fragrances or flavors
2D:
3D:
CAS Number: 1003-03-8
ECHA EC Number: 213-697-3
FDA UNII: 4259VRY3GN
Category: information only not used for fragrances or flavors
IUPAC Name: cyclopentyl amine
InChI : InChI=1/C5H11N/c6-5-3-1-2-4-5/h5H,1-4,6H2
Std.InChI: InChI=1S/C5H11N/c6-5-3-1-2-4-5/h5H,1-4,6H2
InChIKey : NISGSNTVMOOSJQ-UHFFFAOYAM
Std.InChIKey: NISGSNTVMOOSJQ-UHFFFAOYSA-N
SMILES : NC1CCCC1
MDL: MFCD00001380
Molar Refractivity : 26.61 ± 0.3 cm3 (est)
Parachor : 230.0 ± 4.0 cm3 (est)
Index of Refraction : 1.464 ± 0.02 (est)
Surface Tension : 32.5 ± 3.0 dyne/cm (est)
Density : 0.884 ± 0.06 g/cm3 (est)
Polarizability : 10.54 ± 0.5 10-24cm3 (est)

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:Search
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Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search

Physical Properties:

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.86000 to 0.86300 @ 20.00 °C.
Pounds per Gallon - (est).: 7.164 to 7.189
Refractive Index:1.44800 to 1.45100 @ 20.00 °C.
Melting Point: 82.70 °C. @ 760.00 mm Hg
Boiling Point: 108.00 °C. @ 760.00 mm Hg
Vapor Pressure:24.187000 mmHg @ 25.00 °C. (est)
Flash Point: 63.00 °F. TCC ( 17.22 °C. )
logP (o/w): 0.973 (est)
Soluble in:
water, 1.383e+005 mg/L @ 25 °C (est)

Cosmetic Information:

None found

Suppliers:

BOC Sciences
For experimental / research use only.
Cyclopentylamine
EMD Millipore
For experimental / research use only.
Cyclopentylamine
Matrix Scientific
For experimental / research use only.
Cyclopentylamine, 95+%
Noble Molecular Research
For experimental / research use only.
Cyclopentylamine
Santa Cruz Biotechnology
For experimental / research use only.
Cyclopentylamine
Sigma-Aldrich: Aldrich
For experimental / research use only.
Cyclopentylamine 99%
TCI AMERICA
For experimental / research use only.
Cyclopentylamine >99.0%(GC)(T)

Safety Information:

Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Pictogram
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-rat LDLo 100 mg/kg
Biochemical Pharmacology. Vol. 5, Pg. 108, 1960.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
information only not used for fragrances or flavors
Recommendation for cyclopentyl amine usage levels up to:
not for fragrance use.
Recommendation for cyclopentyl amine flavor usage levels up to:
not for flavor use.

Safety References:

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):1003-03-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2906
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
cyclopentanamine
Chemidplus:0001003038
RTECS:GY8452000 for cas# 1003-03-8

References:

cyclopentanamine
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):2906
Pubchem (sid):134979587

Other Information:

(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2921.30.5000
ChemSpider:View

Potential Blenders and core components :

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):

not found in nature

Synonyms:

aminocyclopentane
cyclopentanamine
cyclopentylamine

Articles:

PubMed:Discovery of a cyclopentylamine as an orally active dual NK1 receptor antagonist-serotonin reuptake transporter inhibitor.
PubMed:Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists.
PubMed:A new class of antitumor trans-amine-amidine-Pt(II) cationic complexes: influence of chemical structure and solvent on in vitro and in vivo tumor cell proliferation.
PubMed:Inhibition of Lux quorum-sensing system by synthetic N-acyl-L-homoserine lactone analogous.
PubMed:Nucleophilic reaction of cyclopentylamine on phthalimide derivatives: synthesis and antinociceptive activity of products.
PubMed:Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.
PubMed:Carbocyclic ribosylamines: synthesis of 5-substituted carbocyclic beta-ribofuranosylamines.
PubMed:Zeolite synthesis using degradable structure-directing agents and pore-filling agents.
PubMed:Purification and characterization of a novel cyclohexylamine oxidase from the cyclohexylamine-degrading Brevibacterium oxydans IH-35A.
PubMed:Amino substituted derivatives of 5'-amino-5'-deoxy-5'-noraristeromycin.
PubMed:Inhibition of nucleoside transport proteins by C8-alkylamine-substituted purines.
PubMed:Synthesis of carbocyclic phosphononucleosides.
PubMed:Synthesis of C-5'-nor-dideoxycarbanucleosides structurally related to neplanocin C.
PubMed:[The new antitumor drug cycloplatam: cytotoxicity and DNA interstrand cross-linking].
PubMed:Different modes of inhibition by adamantane amine derivatives and natural polyamines of the functionally reconstituted influenza virus M2 proton channel protein.
PubMed:Synthesis and Crystal Structures of Two Novel Anionic Aluminophosphates: A One-Dimensional Chain, UT-7 ([Al(3)P(5)O(20)H](5-)[C(7)H(13)NH(3)(+)](5)), and a Layer Containing Two Cyclic Amines, UT-8 ([Al(3)P(4)O(16)](3-)[C(4)H(7)NH(3)(+)](2)[C(5)H(10)NH(2)(+)]).
PubMed:[Effect of anti-tumor agents cisplatin and cycloplatam on membrane protein kinase C activity in murine T-lymphocytes].
PubMed:Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo.
PubMed:[Synthesis of tert-butylcyclopentane-fused 1,3-oxazines and 1,3-thiazines].
PubMed:Synthesis, characterization, and antitumor activity of amine platinum(II) and (IV) tellurate complexes.
PubMed:Ammine/amine platinum (II) complexes effective in vivo against murine tumors sensitive or resistant to cisplatin and tetraplatin.
PubMed:Synthesis and antitumor activity of ammine/amine platinum(II) and (IV) complexes.
PubMed:Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites.
PubMed:Preclinical antitumor activity of orally administered platinum (IV) complexes.
PubMed:Influenza virus M2 protein: a molecular modelling study of the ion channel.
PubMed:Antiproliferative effect of complexes of platinum (II) with plasmanyl-(N-acyl)-ethanolamine, an inhibitor of protein kinase C.
PubMed:Effect of the amine non-leaving group on the structure and stability of DNA complexes with cis-[Pt(R-NH2)2(NO3)2].
PubMed:Modulation by polyamines of DNA-dependent DNA polymerase activity from human serum.
PubMed:Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides.
PubMed:Structures of cis-amminedichloro(cyclopentylamine)platinum 0.25-hydrate and potassium trichloro(cyclopentylamine)platinate 0.5-hydrate.
PubMed:Incorporation of cis-dichlorobiscyclopentylamineplatinum (II) into liposomes enhances its uptake by ADJ/PC6A tumour cells: comparative effects of the free and liposome-incorporated drug on the cyclic 3'-5' nucleotide phosphodiesterase activity.
PubMed:Oxidative deamination of alicyclic primary amines by liver microsomes from rats and rabbits.
PubMed:Carbocyclic glycinamide ribonucleotide is a substrate for glycinamide ribonucleotide transformylase.
PubMed:Cytostatic and antitumour properties of a new series of Pt (II) complexes with cyclopentylamine.
PubMed:Enantioselective synthesis of new analogues of neplanocin A.
PubMed:Synthesis and peripheral cardiovascular action of cis- and trans-2-(3,4-dimethoxybenzyl)cyclopentylamine hydrochlorides.
PubMed:Growth in vivo of l5178y-r murine leukaemic cells treated in vitro with cis-dichloro bis-(cyclopentylamine) platinum II.
PubMed:Isobologram analysis of the combined effects of anti-tumour platinum complexes and ionizing radiation on mammalian cells.
PubMed:Central nervous system actions of 2,5-bis(3,4-dimethoxybenzyl) cyclopentyl amine, a peripheral dopamine blocking agent.
PubMed:Toxicity of platinum complexes on hemopoietic precursor cells.
PubMed:Effect of platinum compounds on murine lymphocyte mitogenesis.
PubMed:Antineoplastic activity of platinum complexes of trans-(dl)-1,2-cyclopentanediamine.
PubMed:Response of two strains of L5178Y cells to cis-dichlorobis(cyclopentylamine)platinum(II). II. Differential effects of caffeine.
PubMed:Response of two strains of L5178Y cells to cis-dichlorobis(cyclopentylamine)platinum(II). I. Cross-sensitivity to cis-PAD and UV light.
PubMed:2,5-Bis(3,4-dimethoxybenzyl)cyclopentylamine, a peripheral dopamine blocking agent.
PubMed:Metabolic studies of the nonnutritive sweeteners cyclopentylmethylsulfamate and cyclopentylsulfamate: determination of metabolites in rat urine.
PubMed:Determination of the nonnutritive sweetener sodium cyclopentylsulfamate and three of its metabolites, cyclopentylamine, cyclopentanone, and cyclopentanol, in urine of rats and rabbits.
PubMed:Action of a platinum complex [cis-dichlorobis (cyclopentylamine)-platinum (II)] on Chinese hamster ovary cells in vitro.
PubMed:The effect of combined treatment with a platinum complex and ionizing radiation on chinese hamster ovary cells in vitro.
PubMed:Proceedings: Cis-dichlorobis (cyclopentylamine) platinum II: action on CHO cells in vitro and interaction with ionizing radiation.
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